thalassaemia

n.
a hereditary blood disease, widespread in the Mediterranean countries, Asia, and Africa, in which there is an abnormality in the protein part of the haemoglobin molecule. The affected red cells cannot function normally, leading to anaemia. Other symptoms include enlargement of the spleen and abnormalities of the bone marrow. Individuals inheriting the disease from both parents are severely affected (thalassaemia major), but those inheriting it from only one parent are usually symptom-free. Patients with the major disease are treated with repeated blood transfusions or bone marrow transplantation. The disease can be detected by prenatal diagnosis.

Medical dictionary. 2011.

Look at other dictionaries:

  • thalassaemia — noun an inherited form of anemia caused by faulty synthesis of hemoglobin • Syn: ↑thalassemia, ↑Mediterranean anemia, ↑Mediterranean anaemia • Hypernyms: ↑hypochromic anemia, ↑hypochromic anaemia, ↑monogenic disorder, ↑ …   Useful english dictionary

  • thalassaemia — Cooley s anaemia; n. a hereditary blood disease, widespread in the Mediterranean countries, Asia, and Africa, in which there is an abnormality in the protein part of the haemoglobin molecule. The affected red cells cannot function normally,… …   The new mediacal dictionary

  • thalassaemia — chiefly British variant of thalassemia …   New Collegiate Dictionary

  • thalassaemia — [ˌθalə si:mɪə] (US thalassemia) noun Medicine a hereditary haemolytic disease caused by faulty haemoglobin synthesis, prevalent in Mediterranean, African, and Asian countries. Origin 1930s: from Gk thalassa sea (because first known around the… …   English new terms dictionary

  • thalassaemia — /θæləˈsimiə/ (say thaluh seemeeuh) noun a genetic disease of the blood that may cause severe anaemia, found especially in people from Mediterranean and Middle Eastern countries and in some of the dark skinned peoples of Africa. {Greek thalassa… …   Australian English dictionary

  • thalassaemia major — noun a fatal form of homozygous thalassemia (inherited from both parents) in which there is no hemoglobin; skeletal deformations; heart and spleen and liver enlarged • Syn: ↑Cooley s anemia, ↑Cooley s anaemia, ↑thalassemia major • Hypernyms:… …   Useful english dictionary

  • beta-thalassaemia — / tha lə sēˈmi ə/ noun A genetic disorder of the haemoglobin • • • Main Entry: ↑beta …   Useful english dictionary

  • Cooley's anaemia — thalassaemia …   The new mediacal dictionary

  • талассемия — (thalassaemia; таласс + греч. haima кровь; син. анемия гемолитическая мишеневидно клеточная) наследственная гемолитическая анемия, характеризующаяся нарушением синтеза глобина (белка, входящего в состав гемоглобина); наследуется по рецессивному… …   Большой медицинский словарь

  • Thalassämie — Klassifikation nach ICD 10 D56.0 Alpha Thalassämie D56.1 Beta Thalassämie D56.2 Delta Be …   Deutsch Wikipedia

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