haemophilia

n.
either of two hereditary disorders in which the blood clots very slowly, due to a deficiency of either of two coagulation factors: haemophilia A, due to deficiency of Factor VIII (antihaemophilic factor); or haemophilia B, due to deficiency of Factor IX (Christmas factor). The patient may experience prolonged bleeding following any injury or wound, and in severe cases there is spontaneous bleeding into muscles and joints. Bleeding in haemophilia may be treated by recombinent-DNA-derived Factor VIII or plasma Factor VIII concentrate. Alternatively concentrated preparations of Factor VIII or Factor IX, obtained by freezing fresh plasma, may be administered (see cryoprecipitate). Haemophilia is controlled by a sex-linked gene, which means that it is almost exclusively restricted to males: women can carry the disease - and pass it on to their sons - without being affected themselves. The genes encoding factors VIII and IX have been used in gene therapy trials for haemophilia.
haemophiliac n.

Medical dictionary. 2011.

Look at other dictionaries:

  • Haemophilia — Classification and external resources Deficiency in coagulation factor VIII is the most common cause of haemophilia. ICD 10 D …   Wikipedia

  • Haemophilia B — Classification and external resources ICD 10 D67 ICD 9 286.1 OM …   Wikipedia

  • Haemophilia A — (also spelled Hemophilia A or Hæmophilia A) is a blood clotting disorder caused by a mutation of the factor VIII gene, leading to a deficiency in Factor VIII. It is the most common hemophilia. Inheritance is X linked recessive; hence, males are… …   Wikipedia

  • haemophilia — (US hemophilia) ► NOUN ▪ a medical condition in which the ability of the blood to clot is severely reduced, causing severe bleeding from even a slight injury. DERIVATIVES haemophilic adjective …   English terms dictionary

  • Haemophilia C — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 29376 ICD10 = ICD10|D|68|1|d|65 ICD9 = ICD9|286.2 ICDO = OMIM = 264900 MedlinePlus = eMedicineSubj = ped eMedicineTopic = 964 eMedicine mult = eMedicine2|med|3515 MeshID = D005173 Haemophilia …   Wikipedia

  • haemophilia — n. either of two hereditary disorders in which the blood clots very slowly, due to a deficiency of either of two coagulation factors: haemophilia A, due to deficiency of Factor VIII (antihaemophilic factor); or haemophilia B, due to deficiency of …   The new mediacal dictionary

  • haemophilia — /himəˈfɪliə / (say heemuh fileeuh), / ˈfil / (say feel ), / jə/ (say yuh) noun a blood disorder of males in which clotting occurs abnormally slowly, resulting in excessive bleeding from even minor injuries; haemophilia A is caused by a factor… …   Australian English dictionary

  • haemophilia A — noun hemophilia caused by a congenital deficiency of factor VIII; occurs almost exclusively in men • Syn: ↑hemophilia A, ↑classical hemophilia, ↑classical haemophilia • Hypernyms: ↑hemophilia, ↑haemophilia, ↑bleeder s disease …   Useful english dictionary

  • haemophilia — [[t]hi͟ːməfɪ̱liə[/t]] N UNCOUNT Haemophilia is a medical condition in which a person s blood does not thicken or clot properly when they are injured, so they continue bleeding. (in AM, use hemophilia) …   English dictionary

  • haemophilia B — noun a clotting disorder similar to hemophilia A but caused by a congenital deficiency of factor IX • Syn: ↑hemophilia B, ↑Christmas disease • Hypernyms: ↑hemophilia, ↑haemophilia, ↑bleeder s disease …   Useful english dictionary

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