- a substance that interferes with the development of new blood vessels (angiogenesis). These substances are being investigated for use as anticancer drugs, since growing cancers have a greater need for blood supply than normal tissue and must develop new blood vessels before progressing beyond a very small size. Angiogenesis inhibitors are still at the research stage but have been found capable of eliminating various cancers in mice. Examples are endostatin and angiostatin.
* * *any of a group of drugs that prevent neovascularization of solid tumors.
Medical dictionary. 2011.
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Angiogenesis inhibitor — An angiogenesis inhibitor is a substance that inhibits angiogenesis (the growth of new blood vessels). It can be endogenous or come from outside as drug or a dietary component. Every solid tumor (in contrast to liquid tumors like leukemia) needs… … Wikipedia
angiogenesis inhibitor — A substance that may prevent the formation of blood vessels. In anticancer therapy, an angiogenesis inhibitor prevents the growth of blood vessels from surrounding tissue to a solid tumor … English dictionary of cancer terms
angiogenesis inhibitor — an agent that prevents the development of new blood vessels (angiogenesis) by inhibiting the action of vascular endothelial growth factor. Angiogenesis inhibitors are now used as anticancer drugs, since growing cancers have a greater need for… … The new mediacal dictionary
angiogenesis inhibitor — noun a drug that is designed to prevent the growth of blood vessels that nourish tumors • Hypernyms: ↑medicine, ↑medication, ↑medicament, ↑medicinal drug … Useful english dictionary
Brain-specific angiogenesis inhibitor 1 — Brain specific angiogenesis inhibitor 1, also known as BAI1, is a human gene.cite web | title = Entrez Gene: BAI1 brain specific angiogenesis inhibitor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=575| … Wikipedia
Brain-specific angiogenesis inhibitor — protein Name = brain specific angiogenesis inhibitor 1 caption = width = HGNCid = 943 Symbol = BAI1 AltSymbols = EntrezGene = 575 OMIM = 602682 RefSeq = XM 001130169 UniProt = O14514 PDB = ECnumber = Chromosome = 8 Arm = q Band = 24… … Wikipedia
Brain-specific angiogenesis inhibitor 2 — Brain specific angiogenesis inhibitor 2, also known as BAI2, is a human gene.cite web | title = Entrez Gene: BAI2 brain specific angiogenesis inhibitor 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=576| … Wikipedia
Brain-specific angiogenesis inhibitor 3 — Brain specific angiogenesis inhibitor 3, also known as BAI3, is a human gene.cite web | title = Entrez Gene: BAI3 brain specific angiogenesis inhibitor 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=577| … Wikipedia
Cartilage-derived angiogenesis inhibitor — A cartilage derived angiogenesis inhibitor is an angiogenesis inhibitor produced from cartilage. Examples include the peptide troponin I [cite journal |author=Kern BE, Balcom JH, Antoniu BA, Warshaw AL, Fernández del Castillo C |title=Troponin I… … Wikipedia
Angiogenesis — is a physiological process involving the growth of new blood vessels from pre existing vessels. Though there has been some debate over this, vasculogenesis is the term used for spontaneous blood vessel formation, and intussusception is the term… … Wikipedia