Intermediate in the oxidation of fatty acid s and in the formation of ketone bodies; also formed from two molecules of acetyl-CoA; major role is condensation with acetyl-CoA to form the important β-hydroxy-β-methylglutaryl-CoA. SYN: acetoacetyl-coenzyme A.
- acetoacetyl-CoA reductase [EC] an oxidoreductase catalyzing interconversion of a 3-oxoacyl-CoA and NADPH, and the corresponding d-3-hydroxyacyl-CoA, and NADP+. A step in fatty acid synthesis.
- acetoacetyl-CoA thiolase SYN: acetyl-CoA acetyltransferase.

Medical dictionary. 2011.

Look at other dictionaries:

  • Acetoacetyl-CoA — Chembox new ImageFile=Acetoacetyl coenzyme A.svg ImageSize=300px IUPACName= OtherNames= Section1= Chembox Identifiers CASNo=1420 36 6 PubChem=74 SMILES= MeSHName=acetoacetyl+CoA Section2= Chembox Properties Formula=C25H40N7O18P3S… …   Wikipedia

  • acetoacetyl CoA — ac·e·to·ac·e·tyl CoA (as″ə to asґə təl) (ə seґto as ə tēl″ ko aґ) acetoacetyl coenzyme A …   Medical dictionary

  • Acetoacetyl-CoA hydrolase — In enzymology, an acetoacetyl CoA hydrolase (EC number| is an enzyme that catalyzes the chemical reaction:acetoacetyl CoA + H2O ightleftharpoons CoA + acetoacetateThus, the two substrates of this enzyme are acetoacetyl CoA and H2O,… …   Wikipedia

  • Acetoacetyl-CoA reductase — In enzymology, an acetoacetyl CoA reductase (EC number| is an enzyme that catalyzes the chemical reaction:(R) 3 hydroxyacyl CoA + NADP+ ightleftharpoons 3 oxoacyl CoA + NADPH + H+Thus, the two substrates of this enzyme are (R) 3… …   Wikipedia

  • acetoacetyl CoA thiolase — ac·e·to·ac·e·tyl CoA thi·o·lase (as″ə to asґə təl) (ə seґto as ə tēl″ ko aґ thiґo lās) acetyl CoA C acetyltransferase …   Medical dictionary

  • acetoacetyl-CoA reductase — ac·e·to·ac·e·tyl CoA re·duc·tase (as″ə to asґə təl) (ə seґto as ə tēl″ ko aґ re duk tās) [EC] an enzyme of the oxidoreductase class that catalyzes the reduction of 3 ketoacyl coenzyme A to 3 …   Medical dictionary

  • Acétoacétyl-coenzyme A — Structure de l acétoacétyl coenzyme A Général No CAS …   Wikipédia en Français

  • acetoacetyl-coenzyme A — SYN: acetoacetyl CoA …   Medical dictionary

  • acetoacetyl coenzyme A — ac·e·to·ac·e·tyl co·en·zyme A (as″ə to asґə təl) (ə seґto as ə tēl″ ko enґzīm) a thioester of acetoacetic acid and coenzyme A. It is an important metabolic intermediate in the oxidation of fatty… …   Medical dictionary

  • acetoacetyl-succinic thiophorase — SYN: 3 oxoacid CoA transferase …   Medical dictionary

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