sulfonamide

sul·fon·amide or chiefly Brit sul·phon·amide .səl-'fän-ə-.mīd, -məd; -'fō-nə-.mīd n any of various amides (as sulfanilamide) of a sulfonic acid also SULFA DRUG

* * *

sul·fon·a·mide (səl-fonґə-mīd) 1. an organic compound containing the SO2NH2 group. 2. any of a class of drugs, the sulfa drugs, which are derivatives of sulfanilamide, competitively inhibiting folic acid synthesis in microorganisms and formerly bacteriostatic against gram-positive cocci (streptococci and pneumococci), gram-negative cocci (meningococci and gonococci), gram-negative bacilli (Escherichia coli and shigellae), a wide variety of other bacteria, and some protozoa. Because many strains of bacteria have developed resistance to sulfonamides, particularly to agents used singly, they have largely been supplanted by more effective and less toxic antibiotics, and when used are generally combined with another sulfonamide or other antimicrobial agent.

Medical dictionary. 2011.

Look at other dictionaries:

  • Sulfonamide — may refer to:* Sulfonamide (chemistry) the sulfonamide functional group (organic chemistry) * Sulfonamide (medicine) the group of sulfonamide antibacterial drugs …   Wikipedia

  • sulfonamide — ● sulfonamide nom masculin Nom générique des amides des acides sulfoniques, de formule générale RSO2―NR′R″ …   Encyclopédie Universelle

  • sulfonamide — [sul fän′ə mīd΄, sul fän′əmid] n. [ SULFON(YL) + AMIDE] any of the sulfa drugs, as sulfadiazine, containing the group or the monovalent, negative radical SO2NH2 …   English World dictionary

  • Sulfonamide — Allgemeine Struktur des para Amino benzolsulfonamids eines primären Amins. R ist ein Organylrest …   Deutsch Wikipedia

  • Sulfonamide — Sulfon|amide,   Amidderivate der Sulfonsäuren, allgemeine Formel R SO2 NR R (R = aliphatischer oder aromatischer Rest, R , R = Wasserstoff oder organische Reste). Sulfonamide werden u. a. durch Reaktion von Sulfonylchloriden mit Ammoniak oder… …   Universal-Lexikon

  • sulfonamide — /sul fon euh muyd , mid, sul feuh nam uyd, id/, n. Pharm. See sulfa drug. [1900 05; SULFON(IC ACID) + AMIDE] * * * ▪ chemical compound also spelled  Sulphonamide,         any member of a class of chemical compounds, the amides of sulfonic acids.… …   Universalium

  • sulfonamide — sulfamidas statusas T sritis chemija formulė RSO₂NH₂ atitikmenys: angl. sulfamide; sulfonamide rus. сульфамид …   Chemijos terminų aiškinamasis žodynas

  • sulfonamide — noun Etymology: sulfonic + amide Date: 1881 any of various amides (as sulfanilamide) of a sulfonic acid; also sulfa drug …   New Collegiate Dictionary

  • sulfonamide — (sul fon ah maīd) A chemotherapeutic agent that has the SO2 NH2 group and is a derivative of sulfanilamide …   Dictionary of microbiology

  • sulfonamide — noun a) Any amide of a sulfonic acid RS(=O)NR. b) Any of a group of antibiotics; a sulfa drug …   Wiktionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.