Schick test

Schick test 'shik- n a serological test for susceptibility to diphtheria by cutaneous injection of a diluted diphtheria toxin that causes an area of reddening and induration in susceptible individuals
Schick Béla (1877-1967)
American pediatrician. In 1913 Schick announced his development of the Schick test for susceptibility to diphtheria. The test was a safe, reliable method of detection that eliminated the unnecessary use of sera with serious side effects.

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a test to determine whether a person is susceptible to diphtheria. A small quantity of diphtheria toxin is injected under the skin; a patch of reddening and swelling shows that the person has no immunity and - if at particular risk - should be immunized.
B. Schick (1877-1967), US paediatrician

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(for reactivity or immunity to diphtheria toxin) an intradermal test in which diphtheria toxin equal to one-fiftieth of the minimum lethal dose for a guinea pig is injected into one of the subject's arms (the test site) and an equal quantity of heat-inactivated diphtheria toxin is injected into the other arm (the control site). A positive reaction consists of redness at the test site only, appearing in 24 to 36 hours and persisting for 4 to 5 days, leaving a brown spot on the skin; this indicates lack of immunity to diphtheria. Immunity is indicated by either a pseudoreaction (redness at both sites, usually disappearing in 48 hours without residual pigmentation) or a negative reaction.

Medical dictionary. 2011.

Look at other dictionaries:

  • Schick test — Schick′ test med a diphtheria immunity test in which diphtheria toxoid is injected intracutaneously, nonimmunity being indicated by an inflammation at the injection site • Etymology: 1915–20; after B. Schick …   From formal English to slang

  • Schick test — ☆ Schick test [shik ] n. [after Béla Schick (1877 1967), U.S. pediatrician, born in Hungary, who devised it] a test to determine immunity to diphtheria, made by injecting dilute diphtheria toxin into the skin: if an area of inflammation results,… …   English World dictionary

  • Schick test — noun a skin test for immunity to diphtheria • Hypernyms: ↑skin test * * * ˈshik noun Usage: usually capitalized S Etymology: after Béla Schick died 1967 American pediatrician : a test for susceptibility to diphtheria performed by injecting a… …   Useful english dictionary

  • Schick test — The Schick test, invented between 1910 and 1911, is a test used to determine whether or not a person is susceptible to diphtheria. It was named after its inventor, Béla Schick (1877–1967), a Hungarian born American pediatrician. The test is a… …   Wikipedia

  • Schick test — /ˈʃɪk tɛst/ (say shik test) noun a diphtheria immunity test in which diphtheria toxoid is injected cutaneously, non immunity being characterised by an inflammation at the injection site. {named after Dr Bela Schick, 1877–1967, US paediatrician} …   Australian English dictionary

  • Schick test — n. test discovered by Bela Schick to test susceptibility to diphtheria in which an injection of nontoxic diphtheria is given under the skin to determine whether a patient is immune to diphtheria (if red patch appears on the skin at the point of… …   English contemporary dictionary

  • Schick test — noun Etymology: Béla Schick Date: 1916 a test for susceptibility to diphtheria by cutaneous injection of a diluted diphtheria toxin that causes an area of reddening and induration in susceptible individuals …   New Collegiate Dictionary

  • Schick test — Med. a diphtheria immunity test in which diphtheria toxoid is injected intracutaneously, nonimmunity being indicated by an inflammation at the injection site. [1915 20; named after B. SCHICK] * * * …   Universalium

  • Schick test — a test to determine whether a person is susceptible to diphtheria. A small quantity of diphtheria toxin is injected under the skin; a patch of reddening and swelling shows that the person has no immunity and – if at particular risk – should be… …   The new mediacal dictionary

  • Schick test control — [USP] heat inactivated diphtheria toxin used as a control in the Schick test. Formerly called inactivated diagnostic diphtheria toxin …   Medical dictionary


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