Yeast artificial chromosome (YAC)

A vector (carrier) created and used in the laboratory to clone pieces of DNA. A YAC is constructed from the telomeric, centromeric, and replication origin sequences needed for replication in yeast cells. (The telomere is the end of the chromosome; the centromere is the chromosome region to which spindle fibers attach during cell division; and the replication origin sequences are the spots where the replication of DNA starts.)

Medical dictionary. 2011.

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  • Yeast artificial chromosome — This is a photo of two copies of the Washington University Human Genome YAC Library. Each of the stacks is approximately 12 microtiter plates. Each plate has 96 wells, each with different yeast clones. A yeast artificial chromosome (YAC) is a… …   Wikipedia

  • yeast artificial chromosome — n a chromosome that is used esp. to clone DNA segments longer than those capable of being cloned in bacteria, that is introduced for cloning into a yeast of the genus Saccharomyces (S. cerevisiae), that contains a centromere, a telomere, and a… …   Medical dictionary

  • Yeast Artificial Chromosome — Ein YAC (Yeast Artificial Chromosome) ist ein künstliches Chromosom, welches der Hefe nachempfunden ist. Es dient als Vektor und erlaubt im Gegensatz zu den Cosmiden eine Klonierung von größeren Genomabschnitten. Das erste YAC entstand als… …   Deutsch Wikipedia

  • Yeast Artificial Chromosome — Chromosome artificiel de levure Pour les articles homonymes, voir YAC. Les chromosomes artificiels de levure (Yeast Artificial Chromosomes ou YAC en abrégé) sont très utilisés dans les techniques de biologie moléculaire et le sont, parfois, en… …   Wikipédia en Français

  • yeast artificial chromosome — (YAC) A stretch of DNA that contains all the elements required to propagate a chromosome in yeast and which is used to clone foreign DNA fragments in yeast cells …   Dictionary of microbiology

  • yeast artificial chromosome — Abbreviation: YAC A vector which can be propagated in budding yeast (Saccharamyces pombe), consisting of the minimal elements required for a chromosome to replicate, and allowing for the cloning of large DNA fragments (hundreds of kilobase pairs) …   Glossary of Biotechnology

  • mega yeast artificial chromosome — A yeast artificial chromosome (YAC) which can carry particularly large inserts (up to 1Mbp) standard YACs typically carry inserts of up to 500kbp …   Glossary of Biotechnology

  • Bacterial Artificial Chromosome — Chromosome artificiel bactérien Pour les articles homonymes, voir BAC. Un chromosome bactérien artificiel CBA ou BAC (pour Bacterial Artificial Chromosome), est un vecteur bactérien conçu pour la cartographie et l analyse des génomes complexes… …   Wikipédia en Français

  • Bacterial artificial chromosome — A bacterial artificial chromosome (BAC) is a DNA construct, based on a functional fertility plasmid (or F plasmid), used for transforming and cloning in bacteria, usually E. coli.[1][2] F plasmids play a crucial role because they contain… …   Wikipedia

  • P1-derived artificial chromosome — The P1 derived artificial chromosome are DNA constructs that are derived from the DNA of P1 bacteriophage. They can carry large amounts (about 100 300 kilobases) of other sequences for a variety of bioengineering purposes. It is one type of… …   Wikipedia

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