Y chromosome sex-determining region
- fibrous) gonads without eggs. There is a high incidence of neoplasia (gonadoblastoma and germinoma) in the streak gonads. Translocation (transfer) of the part of the Y chromosome containing SRY to the X chromosome results in XX males — individuals who have XX sex chromosomes but appear male. SRY resides in chromosome band Yp11.3 and encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA binding proteins.
Medical dictionary. 2011.
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