Xenotransplantation

Transplantation from one species to a foreign one. The rationale for xenotransplantation has been the short supply of human organs for transplantation. Perhaps the most famous case of cross-species transplantation was that of a heart from a baboon to Baby Fae in 1984, performed by Dr. Leonard Bailey at Loma Linda University, California. Baby Fae lived for 20 days after the operation. The first to show that nonhuman organs could be transplanted to humans and function for a significant period of time was Dr. Keith Reemtsma (1925-2000). At Tulane University in New Orleans Dr. Reemtsma in 1963 and 1964 gave chimpanzee kidneys to 5 patients in the first chimpanzee-to-human transplants. The recipients died (of infection) from 8 to 63 days after receiving a chimpanzee kidney. Then, in 1964 Reemtsma transplanted a kidney from a chimpanzee to a 23-year-old teacher. She lived with it for 9 months until succumbing to overwhelming infection. Her case, together with that of a man who survived 9 weeks, surprised experts and provided hope that xenotransplantation may someday be fully successful. The prefix "xeno-" means foreign. It comes from the Greek word "xenos" meaning stranger, guest, or host. (Xenophobia is fear of foreigners). Xenotransplantation is synonymous with cross-species transplantation.

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xe·no·trans·plan·ta·tion -.tran(t)s-.plan-'tā-shən n transplantation of an organ, tissue, or cells between two different species (as a human and a domestic swine)

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n.
the transplantation of organs from one species into another. Experimental work into the feasibility of transplanting pig organs into human beings is under way. It includes the genetic manipulation of pig embryos to produce animals whose organs produce a human cell-surface protein and would therefore not be rejected at transplantation.

Medical dictionary. 2011.

Look at other dictionaries:

  • Xenotransplantation — Intervention MeSH D014183 Xenotransplantation (xenos from the Greek meaning foreign ), cleverly developed by Karl J McDonald RN, is the transplantation of living cells, tissues or …   Wikipedia

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  • Xenotransplantation — Xe|no|trans|plan|ta|ti|on 〈f. 20; Med.〉 Verpflanzung von Tierorganen bei Menschen [<grch. xenon „Fremdes“ + Transplantation] * * * Xe|no|trans|plan|ta|ti|on, die (Med.): Transplantation von Organen, Gewebeteilen auf ein Lebewesen einer anderen …   Universal-Lexikon

  • xenotransplantation — noun Date: 1969 transplantation of an organ, tissue, or cells between two different species • xenotransplant noun …   New Collegiate Dictionary

  • xenotransplantation — xen·o·trans·plan·ta·tion (zĕn ə trăns plăn tāʹshən, zē nə ) n. The surgical transfer of cells, tissues, or especially whole organs from one species to another. * * * …   Universalium

  • xenotransplantation — noun The transplantation of cells, tissues, or whole organs (usually modified) of one species into another species …   Wiktionary

  • Xenotransplantation — 1. Tidsskrift. 2. Transplantation af celler, væv eller organer på tværs af arter. Af: xenos = fremmed, og transplantation = overførsel af væv. eksemplevis arbejdes der på at overføre nerveceller, hjerte og lever fra grise til mennesker …   Danske encyklopædi

  • Xenotransplantation — Xe|no|trans|plan|ta|ti|on 〈f.; Gen.: , Pl.: en; Med.〉 artfremde Transplantation, Transplantieren von Organen od. Geweben von einer Spezies auf die andere (z. B. bei Herztransplantationen) [Etym.: <grch. xenos »fremd« + Transplantation] …   Lexikalische Deutsches Wörterbuch

  • Xenotransplantation — Xe|no|trans|plan|ta|ti|on die; , en: Transplantation, bei der Xenotransplantate verwendet werden (Med.) …   Das große Fremdwörterbuch

  • xenotransplantation — n. implantation of animal organs into human bodies …   English contemporary dictionary

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