pulmonary alveolar proteinosis

pulmonary alveolar proteinosis n a chronic disease of the lungs characterized by the filling of the alveoli with proteinaceous material and by the progressive loss of lung function

* * *

a chronic lung disease characterized by dyspnea, productive cough, chest pain, weakness, weight loss, and hemoptysis, and by the filling of the distal alveoli with a bland, eosinophilic, probably endogenous, proteinaceous material that prevents ventilation of affected areas. On computed tomography, the tissue has a characteristic appearance of crazy paving (q.v.).

Pulmonary alveolar proteinosis. The alveoli are filled with a dense, amorphous, protein-lipid granular precipitate; the alveolar walls are normal.


Medical dictionary. 2011.

Look at other dictionaries:

  • Pulmonary alveolar proteinosis — (PAP) is a rare lung disease in which abnormal accumulation of surfactant occurs within the alveoli, interfering with gas exchange. PAP can occur in a primary form or secondarily in the settings of malignancy (especially in myeloid leukemia),… …   Wikipedia

  • pulmonary alveolar proteinosis — ▪ pathology       respiratory disorder caused by the filling of large groups of alveoli with excessive amounts of surfactant, a complex mixture of protein and lipid (fat) molecules. The alveoli are air sacs, minute structures in the lungs in… …   Universalium

  • alveolar proteinosis — pulmonary alveolar p …   Medical dictionary

  • Alveolar lung disease — Alveolar lung disease, also known as airspace disease, is a general term that described edema and exudates in the airspaces of the lung (the acini and alveoli).CausesAlveolar lung disease may be divided into acute or chronic. Causes of acute… …   Wikipedia

  • Pulmonary edema — Classification and external resources Pulmonary edema with small pleural effusions on both sides. ICD 10 J …   Wikipedia

  • Pulmonary hypertension — Pulmonary arterial hypertension Classification and external resources The pulmonary artery receives blood (blue arrow) from the right ventricle of the heart; increased pressure on the artery can impair the function of the right ventricle ICD …   Wikipedia

  • Pulmonary consolidation — Classification and external resources Pneumonia as seen on chest x ray. A: Normal chest x ray. B: Abnormal chest x ray with consolidation from pneumonia in the right lung, middle or inferior lobe (white area, left side of image) …   Wikipedia

  • Pulmonary embolism — Classification and external resources Chest spiral CT scan with radiocontrast agent showing multiple filling defects both at the bifurcation and in the pulmonary arteries. ICD 10 …   Wikipedia

  • Pulmonary surfactant — Diagram of the alveoli with both cross section and external view Pulmonary surfactant is a surface active lipoprotein complex (phospholipoprotein) formed by type II alveolar cells. The proteins and lipids that surfactant comprises have both a… …   Wikipedia

  • proteinosis — A state characterized by disordered protein formation and distribution, particularly as manifested by the deposition of abnormal proteins in tissues. [protein + G. osis, condition] lipoid p. [MIM*247100] a disturbance of lipid metabolism …   Medical dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.