Wilms tumor

A malignant tumor of the kidney in young children. It is also known as nephroblastoma. Wilms tumor is the most common kidney cancer in children and one the most important malignancies in childhood. About 450 new cases of Wilms tumor are diagnosed each year in the U.S. Wilms tumor has a characteristic appearance under the microscope. (It is composed of small spindle cells and other types of tissue, including kidney tubules and glomeruli, and muscle and cartilage.) The treatment of Wilms tumor exemplifies the effectiveness of combining surgery, chemotherapy, and radiation in the treatment of children with cancer. The mortality (death) rate from Wilms tumor was over 60% in the 1950s. However, the survival rate (without recurrence) 2 years after diagnosis now exceeds 90%. Risk factors for the recurrence of Wilms tumor — when it recurs, it tends to stay in the locality not far where it started — include an advanced stage of the tumor (particularly if there is involvement of the lymph nodes near the aorta), an unfavorable microscopic appearance of the tumor, and spillage of tumor cells at the time of surgery. The name Wilms is neither plural nor possessive. It is the family name of Max Wilms, a German surgeon (1867-1918) who described the tumor.

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a rapidly developing malignant mixed tumor of the kidneys, made up of embryonal elements; it usually affects children before the fifth year, but may occur in the fetus and rarely in later life. Called also embryonal adenomyosarcoma or adenosarcoma, embryonal carcinosarcoma or nephroma, and nephroblastoma.

Medical dictionary. 2011.

Look at other dictionaries:

  • Wilms' tumor — Classification and external resources Cut section showing two halves of a nephroblastoma specimen. Note the prominent septa subdividing the sectioned surface and the protrusion of tumor into the renal pelvis, resembling botryoid rhabdomyosarcoma …   Wikipedia

  • Wilms-Tumor — …   Deutsch Wikipedia

  • Wilms' tumor — also Wilms s tumor vilmz (əz ) n a malignant tumor of the kidney that primarily affects children and is made up of embryonic elements called also nephroblastoma Wilms Max (1867 1918) German surgeon. Wilms held professorships at Basel, Switzerland …   Medical dictionary

  • Wilms tumor — or Wilms s tumor «vihlmz or VIHLM zihz», a painless, but malignant tumor in the kidneys, usually in children. ╂[< Max Wilms, 1867 1918, a German surgeon, who described it] …   Useful english dictionary

  • Wilms'tumor — (wĭlmz) n. A malignant tumor of the kidney that is associated with certain genetic abnormalities and chiefly affects young children. Also called nephroblastoma.   [After MaxWilms (1867 1918), German surgeon.] * * * …   Universalium

  • Wilms tumor — Wilms tumor. См. опухоль Вильмса. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Wilms-Tumor — Wịlms Tumor   [nach dem Chirurgen Max Wilms, * 1867, ✝ 1918], Nephroblastom, meist einseitig auftretende bösartige Nierengeschwulst; häufigste Form des Nierenkrebses im Kindesalter (1. 5. Lebensjahr). Der Wilms Tumor stellt einen rasch… …   Universal-Lexikon

  • Wilms tumor — A disease in which malignant (cancer) cells are found in the kidney, and may spread to the lungs, liver, or nearby lymph nodes. Wilms tumor usually occurs in children younger than 5 years old …   English dictionary of cancer terms

  • Wilms' tumor — noun Etymology: Max Wilms died 1918 German surgeon Date: circa 1910 a malignant tumor of the kidney that primarily affects children and is made up of embryonic elements …   New Collegiate Dictionary

  • Wilms' tumor — noun malignant renal tumor of young children characterized by hypertension and blood in the urine and the presence of a palpable mass • Syn: ↑Wilms tumour, ↑adenomyosarcoma, ↑nephroblastoma, ↑embryoma of the kidney • Hypernyms: ↑sarcoma …   Useful english dictionary

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