- protein kinase n any of a class of allosteric enzymes that possess a catalytic subunit which transfers a phosphate from ATP to one or more amino acid residues (as serine, threonine, or tyrosine) in a protein's side chain resulting in a conformational change affecting protein function, that play a role in regulating intracellular processes, and that include many which are activated by the binding of a second messenger (as cyclic AMP)
* * *pro·tein ki·nase (proґtēn kiґnās) [EC 2.7.10â€“99] any of several groups of enzymes of the transferase class that catalyze the phosphorylation of serine, threonine, tyrosine, or histidine groups in enzymes and other proteins, using ATP as a phosphate donor. Specific protein kinases regulate by phosphorylation enzymes catalyzing key reactions in processes such as glycogen turnover, cholesterol biosynthesis, and amino acid transformations. Further subdivisions include protein-tyrosine kinases [EC 2.7.10], protein-serine/threonine kinases [EC 2.7.11], dual-specificity kinases [EC 2.7.12], and protein-histidine kinases [EC 2.7.13].
Medical dictionary. 2011.
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Protein kinase D1 — Protein kinase D1, also known as PRKD1, is a human gene.cite web | title = Entrez Gene: PRKD1 protein kinase D1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=5587| accessdate = ] PBB Summary section title … Wikipedia
Protein kinase R — (Eukaryotic translation initiation factor 2 alpha kinase 2) is a protein protecting against viral infections. EIF2AK2 is its human gene.cite web | title = Entrez Gene: EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2| url =… … Wikipedia
Protein kinase N1 — Protein kinase N1, also known as PKN1, is a human gene.cite web | title = Entrez Gene: PKN1 protein kinase N1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=5585| accessdate = ] PBB Summary section title … Wikipedia
Protein kinase C — ( PKC , EC number|220.127.116.11) is a family of protein kinases consisting of 10 isozymes.cite journal | author = Mellor H, Parker PJ | title = The extended protein kinase C superfamily | journal = Biochem. J. | volume = 332 ( Pt 2) | issue = | pages … Wikipedia
Protein kinase Mζ — (also called PKMζ or PKMzeta) is the independent catalytic domain of protein kinase Cζ and, lacking an autoinhibitory regulatory domain of the full length PKCζ, is constitutively active. This constitutive or autonomous activity allows the kinase… … Wikipedia
protein kinase C — sē n any of a group of isoenzymes of protein kinase that modify the conformation and activity of various intracellular proteins by catalyzing the phosphorylation of specific serine or threonine amino acid residues in the polypeptide chains of the … Medical dictionary
Protein kinase A — In cell biology, Protein kinase A (PKA) refers to a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA is also known as cAMP dependent protein kinase (EC 18.104.22.168). Protein kinase A has several functions… … Wikipedia
Protein kinase — A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation). This class of protein may further be separated into subsets as in the case of protein kinase C PKC alpha, PKC beta,… … Wikipedia
protein kinase C — noun Date: 1981 a protein kinase that catalyzes the phosphorylation of specific serine or threonine amino acid residues … New Collegiate Dictionary
protein kinase A — Cyclic AMP dependent protein kinase … Dictionary of molecular biology