Papanicolaou smear

Pa·pa·ni·co·laou smear .päp-ə-'nē-kə-.lau̇-, .pap-ə-'nik-ə- n PAP SMEAR
Papanicolaou George Nicholas (1883-1962)
American anatomist and cytologist. Papanicolaou devoted his medical research almost entirely to the physiology of reproduction and exfoliative cytology. In 1917 he began studying the vaginal discharge of the guinea pig, examining specifically the histological and physiological changes that occur during a typical estrous cycle. In 1923 he turned to the cytological examination of the vaginal fluid of women as a way of detecting uterine cancer. In 1943 he published his findings after studying 179 cases of uterine cancer. His monograph Diagnosis of Uterine Cancer by Vaginal Smear treated a variety of physiological and pathological states, including abortion, amenorrhea, ectopic pregnancy, endometrial hyperplasia, menopause, the menstrual cycle, prepuberty, and puerperium. The Papanicolaou smear rapidly achieved wide acceptance as a means of cancer diagnosis.

Medical dictionary. 2011.

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  • Papanicolaou smear — noun a sample of secretions and superficial cells of the uterine cervix and uterus; examined with a microscope to detect any abnormal cells • Syn: ↑cervical smear, ↑Pap smear • Hypernyms: ↑smear, ↑cytologic smear, ↑cytosmear • Part Holonyms …   Useful english dictionary

  • Papanicolaou smear — /pæpəˈnɪkəlaʊ smɪə / (say papuh nikuhlow smear) noun → Pap smear. {from George Papanicolaou, 1883–1962, US scientist, who invented this test} …   Australian English dictionary

  • Papanicolaou smear — noun Etymology: George N. Papanicolaou died 1962 American medical scientist Date: 1950 Pap smear …   New Collegiate Dictionary

  • smear test — noun a method of examining stained cells in a cervical smear for early diagnosis of uterine cancer • Syn: ↑Pap test, ↑Papanicolaou test • Hypernyms: ↑diagnostic test, ↑diagnostic assay • Part Meronyms: ↑cervical smear, ↑ …   Useful english dictionary

  • Papanicolaou test — noun a method of examining stained cells in a cervical smear for early diagnosis of uterine cancer • Syn: ↑Pap test, ↑smear test • Hypernyms: ↑diagnostic test, ↑diagnostic assay • Part Meronyms: ↑cervical smear, ↑ …   Useful english dictionary

  • Papanicolaou stain — showing a low grade squamous intraepithelial lesion (LSIL). Pap test. Papanicolaou stain (also Papanicolaou s stain and Pap stain) is a multichromatic staining histological technique developed by George Papanikolaou, the father of cytopathology.… …   Wikipedia

  • Papanicolaou test — n PAP SMEAR * * * (Pap test) see cervical smear G. N. Papanicolaou (1883 1962), Greek physician, anatomist, and cytologist …   Medical dictionary

  • smear test — Papanicolaou t …   Medical dictionary

  • smear — A thin specimen for examination; it is usually prepared by spreading material uniformly onto a glass slide, fixing it, and staining it before examination. alimentary tract s. a group of …   Medical dictionary

  • Papanicolaou, George Nicolas — SUBJECT AREA: Medical technology [br] b. 13 May 1883 Kimi, Greece d. 19 February 1962 Miami, Florida, USA [br] Greek physician and pathological anatomist, developer of the Papanicolaou cytological smear test (Pap test). [br] Of a medical family,… …   Biographical history of technology

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