minimum lethal dose

minimum lethal dose n the smallest dose experimentally found to kill any one animal of a test group

* * *

(MLD) 1. the smallest amount of a toxic substance that can cause the death of a laboratory animal. 2. in preparing diphtheria toxoid, the smallest quantity of diphtheria toxin that will kill a guinea pig of 250 g weight in four to five days when injected subcutaneously.

Medical dictionary. 2011.

Look at other dictionaries:

  • Minimum lethal dose — (LDmin) is the least amount of drug that can produce death in a given animal species under controlled conditions.[1] For the concept Median Lethal Dose (MLD, also LD50), see Median lethal dose.[2] Notes ^ M03933. IUPAC Compendium of Chemical… …   Wikipedia

  • minimum lethal dose — the smallest amount of a lethal compound sufficient to kill all of the test animals …   Dictionary of ichthyology

  • minimum lethal dose — noun : the smallest dose experimentally found to kill any one animal of a test group …   Useful english dictionary

  • lethal dose — the amount of an agent, such as a toxin or radiation, that will or may be sufficient to cause death. See also median lethal d. and minimum lethal d. Called also fatal d. Cf. L+ d …   Medical dictionary

  • Median lethal dose — This article is about the toxicological term. For the album by Mudvayne, see L.D. 50 (album). For other uses, see LD50 (disambiguation). In toxicology, the median lethal dose, LD50 (abbreviation for “Lethal Dose, 50%”), LC50 (Lethal Concentration …   Wikipedia

  • Dose Létale 50 — La dose létale 50 ou DL50 (LD50 en anglais pour Lethal Dose 50) ou CL50 (concentration létale 50) est un indicateur quantitatif de la toxicité d une substance. Cette notion s applique également aux irradiations. Cet indicateur mesure la dose de… …   Wikipédia en Français

  • Dose létale 50 — La dose létale 50 ou DL50 (LD50 en anglais pour Lethal Dose 50) ou CL50 (concentration létale 50) est un indicateur quantitatif de la toxicité d une substance. Cette notion s applique également aux irradiations. Cet indicateur mesure la dose de… …   Wikipédia en Français

  • Lethal white syndrome — (LWS), also called overo lethal white syndrome (OLWS), lethal white overo (LWO), and overo lethal white foal syndrome (OLWFS), is an autosomal genetic disorder most prevalent in the American Paint Horse. Affected foals are born after the full 11… …   Wikipedia

  • dose — 1. The quantity of a drug or other remedy to be taken or applied all at one time or in fractional amounts within a given period. Cf.:dosage (2). 2. In nuclear medicine, amount of energy absorbed per unit mass of irradiated material (absorbed d.) …   Medical dictionary

  • lethal unit — the estimated minimum dose needed to kill 100% of test fish in a given time period …   Dictionary of ichthyology

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.