Time, prothrombin


Time, prothrombin
A clotting test, the prothrombin time is done to test the integrity of part of the clotting scheme. The prothrombin time is commonly used as a method of monitoring the accuracy of blood thinning treatment (anticoagulation) with COUMADIN. Familiarly called the "pro time," the test is the time needed for clot formation after a substance called thromboplastin (+ calcium) has been added to plasma. Prothrombin is a coagulation (clotting) factor needed for the normal clotting of blood. There is a cascade of biochemical events that leads to the formation of the final clot. In this cascade, prothrombin is a precursor to thrombin. Because prothrombin comes before thrombin, it is called prothrombin.

Medical dictionary. 2011.

Look at other dictionaries:

  • time — 1. That relation of events which is expressed by the terms past, present, and future, and measured by units such as minutes, hours, days, months, or years. 2. A certain period during which something definite or determined is done. SYN: tempus (2) …   Medical dictionary

  • Prothrombin — is a coagulation (clotting) factor. It is needed for the normal clotting of blood. There is a cascade of biochemical events that leads to the formation of the final clot. In this cascade, prothrombin is a precursor to thrombin. Because… …   Medical dictionary

  • prothrombin test — prothrombin time. 2. two stage prothrombin time t …   Medical dictionary

  • Prothrombin complex concentrate — (PCC) (trade name Beriplex or Octaplex[1]) is a combination of blood clotting factors II, VII, IX and X, as well as protein C and S.[1] It reverses the effect of warfarin (a coumarin anti coagulant) and is used in cases of significant bleeding in …   Wikipedia

  • Prothrombin time — The prothrombin time (PT) and its derived measures of prothrombin ratio (PR) and international normalized ratio (INR) are measures of the extrinsic pathway of coagulation. They are used to determine the clotting tendency of blood, in the measure… …   Wikipedia

  • Prothrombin time — A clotting test, the prothrombin time is done to test the integrity of part of the clotting scheme. The prothrombin time is commonly used as a method of monitoring the accuracy of blood thinning treatment (anticoagulation) with COUMADIN.… …   Medical dictionary

  • prothrombin time — noun : the time required for a particular specimen of prothrombin to induce blood plasma clotting under standardized conditions in comparison with a time of between 11.5 and 12 seconds for normal human blood …   Useful english dictionary

  • prothrombin time — PT the time taken for blood clotting to occur in a sample of blood to which calcium and thromboplastin have been added. A prolonged PT (compared with a control sample) indicates a deficiency of coagulation factors, which – with calcium and… …   The new mediacal dictionary

  • one-stage prothrombin time — prothrombin t …   Medical dictionary

  • PRO-TIME — Prothrombin Time (Medical » Physiology) …   Abbreviations dictionary


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.