Thiamine is vitamin B1. Thiamine acts as a coenzyme in the metabolism of the body. Deficiency of thiamine leads to beriberi, a disease affecting the heart and nervous system. The word "vitamin" was coined in 1911 by the Warsaw-born biochemist Casimir Funk (1884-1967). At the Lister Institute in London, Funk isolated a substance that prevented nerve inflammation (neuritis) in chickens raised on a diet deficient in that substance. He named the substance "vitamine" because he believed it was necessary to life and it was a chemical amine. The "e" at the end was later removed when it was recognized that vitamins need not be amines. The letters (A, B, C and so on) were assigned to the vitamins in the order of their discovery. The one exception was vitamin K which was assigned its "K" from "Koagulation" by the Danish researcher Henrik Dam. The vitamins include: {{}}Vitamin A: Retinol. Carotene compounds responsible for transmitting light sensation in the retina of the eye. Deficiency leads to night blindness. Beta carotene: An antioxidant which protects cells against oxidation damage that can lead to cancer. Beta carotene is converted, as needed, to vitamin A. Food sources of beta carotene include vegetables such as carrots, sweet potatoes, spinach and other leafy green vegetables; and fruit such as cantaloupes and apricots. Excessive carotene in the diet can temporarily yellow the skin, a condition called carotenemia, commonly seen in infants fed largely mushed carrots. Vitamin B2: Riboflavin, essential for the reactions of coenzymes. Deficiency causes inflammation of the lining of the mouth and skin. Vitamin B3: Niacin, an essential part of coenzymes of body metabolism. Deficiency causes inflammation of the skin, vagina, rectum and mouth, as well as mental slowing. Vitamin B6: Pyridoxine, a cofactor for enzymes. Deficiency leads to inflammation of the skin and mouth, nausea, vomiting, dizziness , weakness and anemia. Folate (folic acid): Folic acid is an important factor in nucleic acid synthesis (the genetic material). Folate deficiency leads to megaloblastic anemia. Vitamin B12: An essential factor in nucleic acid synthesis (the genetic material of all cells). Deficiency leads to megaloblastic anemia, as can be seen in pernicious anemia. Vitamin C: Ascorbic acid, important in the synthesis of collagen, the framework protein for tissues of the body. Deficiency leads to scurvy, characterized by fragile capillaries, poor wound healing, and bone deformity in children. Vitamin D: A steroid vitamin which promotes absorption and metabolism of calcium and phosphorus. Under normal conditions of sunlight exposure, no dietary supplementation is necessary because sunlight promotes adequate vitamin D synthesis in the skin. Deficiency can lead to osteomalacia in adults and bone deformity (rickets) in children. Vitamin E: Deficiency can lead to anemia. Vitamin K: An essential factor in the formation of blood clotting factors. Deficiency can lead to abnormal bleeding.
* * *
SYN: thiamin.

* * *

thi·a·mine 'thī-ə-mən, -.mēn also thi·a·min -mən n a vitamin C12H17N4OSCl of the B complex that is an amino hydroxy quaternary ammonium water-soluble salt containing a thiazole ring and a pyrimidine ring, that occurs widely both free (as in the germs of cereals and hulls of grain) and combined (as in yeast and in animal tissues like liver, kidneys, and heart) but is usu. synthesized commercially, that functions in the body as a cocarboxylase and is essential for carbohydrate metabolism and for normal functioning of the nervous system, and that is used in nutrition (as in vitamin preparations and in enriching flour and bread) and in medicine called also vitamin B1

* * *

thi·a·mine (thiґə-min) vitamin B1>, a heat-labile, water-soluble bicyclic compound comprising a substituted pyrimidine linked to a thiazole moiety. It is found particularly in pork, organ meats, legumes, nuts, and whole grain or enriched cereals and breads. The active form is thiamine pyrophosphate (q.v.). Deficiency of the vitamin can result in beriberi and is a factor in alcoholic neuritis and Wernicke-Korsakoff syndrome. Written also thiamin.

Medical dictionary. 2011.

Look at other dictionaries:

  • thiamine — [ tjamin ] n. f. • mil. XXe; de thi(o) et amine ♦ Biochim. Vitamine B1. Administration de thiamine dans le traitement des polynévrites. ● thiamine nom féminin Synonyme de vitamine B1. ● thiamine (synonymes) nom féminin Synonymes …   Encyclopédie Universelle

  • thiamine — thiamine. См. тиамин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • thiamine — (also thiamin) ► NOUN ▪ vitamin B1, a compound found in unrefined cereals, beans, and liver, a deficiency of which causes beriberi. ORIGIN from Greek theion sulphur …   English terms dictionary

  • thiamine — [thī′əminthī′ə min, thī′əmēn΄] n. [< THI + (VIT)AMIN] a white, crystalline B vitamin, C12H17ClN4OS, found in the outer coating of cereal grains, green peas, beans, egg yolk, liver, etc., and also prepared synthetically; vitamin B1: a… …   English World dictionary

  • Thiamine — For the similarly spelled nucleobase, see thymine. Thiamine chloride …   Wikipedia

  • Thiamine — Vitamine B1 Vitamine B1 Général Nom IUPAC …   Wikipédia en Français

  • thiamine — /thuy euh min, meen /, n. Biochem. a white, crystalline, water soluble compound of the vitamin B complex, containing a thiazole and a pyrimidine group, C12H17ClN4OS, essential for normal functioning of the nervous system, a deficiency of which… …   Universalium

  • thiamine — also thiamin noun Etymology: thiamine alteration of thiamin, from thi + amin (as in vitamin) Date: 1937 a vitamin C12H17N4OSCl of the vitamin B complex that is essential to normal metabolism and nerve function and is widespread in plants and… …   New Collegiate Dictionary

  • thiamine — мед. тиамин (thiamine – витамин B1)  Водорастворимый витамин.   Участвует в процессе превращения глюкозы в энергию.   Необходим для нормальной работы нервной системы.  Тиамин содержится в основном в зерновых продуктах, отрубях.  Им богаты хлеб из …   Универсальный дополнительный практический толковый словарь И. Мостицкого

  • thiamine — thiamin UK [ˈθaɪəmɪn] / US or thiamine UK [ˈθaɪəmiːn] / US [ˈθaɪəˌmɪn] noun [uncountable] medical a natural chemical in many types of food that your body uses to make your nerves work correctly. It belongs to the vitamin B group …   English dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.