Test, prostate specific antigen
- BPH), an increase in the size of the prostate that typically occurs with aging. Infection of the prostate gland (prostatitis) is another relatively common cause of an elevated PSA. Other confounding conditions that can increase PSA include ischemia or infarction, urethral instrumentation, and urinary retention, and prostate biopsy. The PSA test has other limitations. A small proportion of prostate cancers do not produce a detectable increase in blood PSA, even with advanced disease. Many early cancers will also not produce enough PSA to cause a significantly abnormal blood level. It is therefore important not to rely only on blood PSA testing. The most useful additional test is a physical prostate exam known as the digital rectal exam (DRE).
Medical dictionary. 2011.
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