erythroblastosis fetalis

erythroblastosis fe·ta·lis -fi-'tal-əs n a hemolytic disease of the fetus and newborn that is characterized by an increase in circulating erythroblasts and by jaundice and that occurs when the system of an Rh-negative mother produces antibodies to an antigen in the blood of an Rh-positive fetus which cross the placenta and destroy fetal red blood cells called also hemolytic disease of the newborn, Rh disease

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erythroblastosis neonatorum a type of hemolytic anemia of the fetus or newborn infant, caused by the transplacental transmission of maternally formed antibody, usually secondary to an incompatibility between the blood group of the mother and that of her offspring. The most common and frequently fatal type occurs when the baby or fetus is Rh positive and the mother is Rh negative. Another type is found in babies or fetuses of blood groups A and B whose mothers have type O blood; it is much milder than the Rh type because anti-A and anti-B antibodies only occasionally cross the placenta. Characteristics include accelerated destruction of erythrocytes, causing jaundice, increased red cell regeneration (nucleated red cells in the blood), and hepatosplenomegaly. In infants with severe jaundice, kernicterus may result. The most severe form is hydrops fetalis. Called also congenital or hemolytic anemia of newborn and hemolytic disease of newborn.

Medical dictionary. 2011.

Look at other dictionaries:

  • erythroblastosis fetalis — erythroblastosis fetalis. См. эритробластоз плода. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • erythroblastosis fetalis — or hemolytic disease of the newborn Anemia in an infant, caused when a pregnant woman produces antibodies to an antigen in her fetus s red blood cells. An Rh negative woman (see Rh blood group system) with an Rh positive fetus whose ABO blood… …   Universalium

  • erythroblastosis fetalis — noun A medical condition where an rh negative mothers antibodies attack the red blood cells of an rh positive fetus. See Also: erythroblastosis, erythroblastosis neonatorum, hemolytic disease …   Wiktionary

  • erythroblastosis fetalis — noun Etymology: New Latin, fetal erythroblastosis Date: circa 1934 a hemolytic disease of the fetus and newborn that occurs when the system of an Rh negative mother produces antibodies to an antigen in the blood of an Rh positive fetus which… …   New Collegiate Dictionary

  • erythroblastosis fetalis — noun severe anemia in newborn babies; the result of Rh incompatibility between maternal and fetal blood; typically occurs when the child of an Rh negative mother inherits Rh positive blood from the father; can be diagnosed before birth by… …   Useful english dictionary

  • erythroblastosis fetalis — Severe haemolytic disease of the neonate as a result of transplacental passage of maternal antibodies mainly directed against Rhesus blood group antigens …   Dictionary of molecular biology

  • erythroblastosis fe|tal|is — «fih TAL ihs», erythroblastosis of the fetus: »Erythroblastosis fetalis occurs in about 10 per cent of the cases when an Rh negative mother is pregnant with an Rh positive baby (New York Times). ╂[< New Latin erythroblastosis fetalis fetal… …   Useful english dictionary

  • fetalis — see ERYTHROBLASTOSIS FETALIS, HYDROPS FETALIS …   Medical dictionary

  • erythroblastosis neonatorum — erythroblastosis ne·o·na·to·rum .nē ə nə tōr əm n ERYTHROBLASTOSIS FETALIS …   Medical dictionary

  • erythroblastosis — [fi tal′ise rith΄rō blas tō′sis] n. 1. the appearance of immature, nucleate red blood cells in the circulating blood 2. a disease of the developing fetus and newborn infant, characterized by a hemolytic anemia and jaundice and caused by an… …   English World dictionary

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