diabetes mellitus

diabetes mel·li·tus -'mel-ət-əs n a variable disorder of carbohydrate metabolism caused by a combination of hereditary and environmental factors and usu. characterized by inadequate secretion or utilization of insulin, by excessive urine production, by excessive amounts of sugar in the blood and urine, and by thirst, hunger, and loss of weight see type 1 DIABETES, type 2 DIABETES

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a disorder of carbohydrate metabolism in which sugars in the body are not oxidized to produce energy due to lack of the pancreatic hormone insulin. The accumulation of sugar leads to its appearance in the blood (hyperglycaemia), then in the urine; symptoms include thirst, loss of weight, and the excessive production of urine. The use of fats as an alternative source of energy leads to disturbances of the acid-base balance, the accumulation of ketones in the bloodstream (ketosis), and eventually to diabetic coma. There appears to be an inherited tendency to diabetes; the disorder may be triggered by various factors, including physical stress.
Diabetes that starts in childhood or adolescence is usually more severe than that beginning in middle or old age. It is known as type 1 (or insulin-dependent) diabetes mellitus as patients have little or no ability to produce the hormone and are entirely dependent on insulin injections for survival. In type 2 (noninsulin-dependent or maturity-onset) diabetes mellitus, which usually occurs after the age of 40 but can develop in young people (see maturity-onset diabetes of the young), the pancreas retains some ability to produce insulin but this is inadequate for the body's needs; alternatively, the body becomes resistant to the effects of insulin. Patients may require treatment with oral hypoglycaemic drug or insulin. In both types of diabetes the diet must be carefully controlled, with adequate carbohydrate for the body's needs. Lack of balance in the diet or in the amount of insulin taken leads to hypoglycaemia. Long-term complications of diabetes include damage to blood vessels, which can affect the eyes (diabetic retinopathy), kidneys (diabetic nephropathy), and nerves (diabetic neuropathy).

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(DM) a chronic syndrome of impaired carbohydrate, protein, and fat metabolism owing to insufficient secretion of insulin or to target tissue insulin resistance. It occurs in two major forms: type 1 d. mellitus and type 2 d. mellitus, which differ in etiology, pathology, genetics, age of onset, and treatment.

Medical dictionary. 2011.

Look at other dictionaries:

  • Diabetes mellitus — Diabetes redirects here. For other uses, see Diabetes (disambiguation). Diabetes mellitus Classification and external resources Universal blue circle symbol for diabetes.[1] …   Wikipedia

  • Diabetes mellitus — Saltar a navegación, búsqueda Diabetes mellitus Clasificación y recursos externos Aviso médico …   Wikipedia Español

  • Diabetes mellitus — diabetes di a*be tes, n. [NL., from Gr. ?, fr. ? to pass or cross over. See {Diabase}.] (Med.) Any of several diseases which is attended with a persistent, excessive discharge of urine; when used without qualification, the term usually refers to… …   The Collaborative International Dictionary of English

  • diabetes mellitus — Enfermedad endocrina caracterizada por una reducción parcial o total de la secreción de insulina (diabetes de tipo 1) o por una resistencia a la insulina (diabetes de tipo 2) que se traduce en unos elevados niveles de glucosa en sangre… …   Diccionario médico

  • diabetes mellitus — [mə līt′əs] n. 〚ModL, lit., honey diabetes < L mellitus, of honey, honeyed < mel, honey: see MILDEW〛 a chronic form of diabetes involving an insulin deficiency and characterized by an excess of sugar in the blood and urine, and by hunger, thirst …   Universalium

  • Diabetes mellitus — Diabetes mellitus, es un grupo de enfermedades metabólicas caracterizadas por hiperglucemia (aumento de los niveles de glucosa en sangre), resultado de defectos en la secreción de insulina, en su acción o ambos. Se trata de una compleja… …   Enciclopedia Universal

  • diabetes mellitus — [mə līt′əs] n. [ModL, lit., honey diabetes < L mellitus, of honey, honeyed < mel, honey: see MILDEW] a chronic form of diabetes involving an insulin deficiency and characterized by an excess of sugar in the blood and urine, and by hunger,… …   English World dictionary

  • diabetes mellitus — diabetes mellitus. См. сахарный диабет. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Diabetes mellitus — Diabetes mellitus, Zuckerkrankheit ⇒ Insulin …   Deutsch wörterbuch der biologie

  • Diabetes mellitus — Klassifikation nach ICD 10 E10 Primär insulinabhängiger Diabetes mellitus (Typ 1 Diabetes) E11 Nicht primär insulinabhängiger Diabetes mellitus (Typ 2 Diabetes) …   Deutsch Wikipedia

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