cytomegalic inclusion disease

cytomegalic inclusion disease n a severe disease esp. of newborns that is caused by the cytomegalovirus and usu. affects the salivary glands, brain, kidneys, liver, and lungs called also inclusion disease

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cytomegalovirus disease any of a group of diseases caused by cytomegalovirus infection, marked by characteristic inclusion bodies in enlarged infected cells. They were formerly mainly congenital, acquired by a fetus in utero from the mother or during passage through the birth canal; most such infants are asymptomatic, but in some there may be hepatosplenomegaly, jaundice, chorioretinitis, purpura, and severe central nervous system sequelae. The incidence has gone up with the increase in immunodeficient states; the virus can be transmitted via respiratory droplets, tissue or blood donation, or sexual contact. Serious complications can occur in immunocompromised patients. The most common conditions are cytomegalovirus colitis, encephalitis, mononucleosis, pneumonia, and retinitis.

Medical dictionary. 2011.

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