- blast crisis n the terminal stage of chronic myelogenous leukemia that is characterized by a marked increase in the proportion of blast cells, by fever and pain in the bones, and by increased severity of anemia, thrombocytopenia, and splenomegaly called also blastic crisis
* * *a sudden, severe transformation of chronic myelogenous leukemia to a more aggressive course; the proportion of blast cells increases rapidly, and the clinical picture resembles that in acute myelogenous leukemia.
Medical dictionary. 2011.
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