Selective Estrogen-Receptor Modulator (SERM)
- A "designer estrogen" which possesses some, but not all, of the actions of estrogen. For example, raloxifene (trade name EVISTA) is classified as a SERM because it prevents bone loss (like estrogen) and lowers serum cholesterol (like estrogen) but (unlike estrogen) does not stimulate the endometrial lining of the uterus.
Medical dictionary. 2011.
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Selective estrogen receptor modulator — Selective Estrogen Receptor Modulators (SERMs) are a class of medication that acts on the estrogen receptor.cite journal |author=Riggs BL, Hartmann LC|title=Selective estrogen receptor modulators mechanisms of action and application to clinical… … Wikipedia
selective estrogen receptor modulator — n any of a class of drugs (as raloxifene or tamoxifen) that bind with estrogen receptors and act as estrogen agonists in some tissues and estrogen antagonists in other tissues abbr. SERM * * * (SERM) an agent that activates some estrogen… … Medical dictionary
selective estrogen receptor modulator — SERM. A drug that acts like estrogen on some tissues but blocks the effect of estrogen on other tissues. Tamoxifen and raloxifene are SERMs. Also called SERM … English dictionary of cancer terms
selective (o)estrogen receptor modulator — SERM a drug that has oestrogen like activity in some tissues and an anti oestrogenic effect in others, depending on the manner of its binding with the oestrogen receptors. Tamoxifen was the first SERM to be introduced. Because of its activity as… … The new mediacal dictionary
SERM — Abbreviation for selective estrogen receptor modulator. * * * selective estrogen receptor modulator * * * SERM abbr selective estrogen receptor modulator * * * selective estrogen receptor modulator … Medical dictionary
SERM — Selective estrogen receptor modulator. A drug that acts like estrogen on some tissues but blocks the effect of estrogen on other tissues. Tamoxifen and raloxifene are SERMs. Also called selective estrogen receptor modulator … English dictionary of cancer terms
SERM — Selective Estrogen Receptor Modulator (Medical » Physiology) Selective Estrogen Receptor Modulator (Medical » Laboratory) … Abbreviations dictionary
SERM — may refer to:* Selective estrogen receptor modulator * Structured Entity Relationship Model * Search Engine Reputation Management … Wikipedia
SERM — • selective estrogen receptor modulator … Dictionary of medical acronyms & abbreviations
modulator — That which regulates or adjusts. selective estrogen receptor m. (SERM) pharmaceutical agent with selective estrogen receptor affinity; current preparations have a primary effect on bone and … Medical dictionary