Ribozyme

An RNA molecule that can catalyze its own chemical reactions.
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A nonprotein biocatalyst; several cleave precursors of tRNA to yield functional tRNAs; others act on rRNA; plays a key role in intron splicing events. SYN: organic catalyst (1), RNA enzyme. [ribonucleic acid + -zyme]

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ri·bo·zyme 'rī-bə-.zīm n a molecule of RNA that functions as an enzyme (as by catalyzing the cleavage of other RNA molecules)

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n.
an RNA molecule that can act as an enzyme, catalysing changes to its own molecular structure (before the discovery of ribozymes it was assumed that all enzymes were proteins). Since replication of DNA and RNA cannot occur without enzymes, and since protein enzymes can only be produced by DNA coding, the question arose as to how nucleic acid molecules were able to replicate in the early stages of evolution. The discovery of ribozymes appears to resolve the enigma. Research is currently being undertaken to exploit the ability of genetically engineered ribozymes to destroy the RNA of HIV (the AIDS virus).

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ri·bo·zyme (riґbo-zīm″) [ribonucleic acid + -zyme] an RNA molecule with catalytic activity; different classes exist, and the reactions they catalyze may be intramolecular, e.g., self-splicing, or intermolecular, e.g., maturation of tRNA molecules. Secondary and tertiary structure is important to activity.

Medical dictionary. 2011.

Look at other dictionaries:

  • ribozyme — [ ribozim ] n. m. • 1982; de ribo et (en)zyme ♦ Biochim. Molécule d A. R. N. capable de couper, coller, assembler d autres morceaux d A. R. N. selon un mode de fonctionnement typiquement enzymatique. ● ribozyme nom masculin (de ribosome et… …   Encyclopédie Universelle

  • ribozyme — [rī′bə zīm΄] n. a molecule of RNA that acts as an enzyme, used in genetic research and gene therapy …   English World dictionary

  • Ribozyme — A ribozyme (from ribonucleic acid enzyme, also called RNA enzyme or catalytic RNA) is an RNA molecule that catalyzes a chemical reaction. Many natural ribozymes catalyze either the hydrolysis of one of their own phosphodiester bonds, or the… …   Wikipedia

  • Ribozyme — Le ribozyme en tête de marteau présent dans le génome de certains viroïdes de plantes Les ribozymes sont des ARN qui possèdent la propriété de catalyser une réaction chimique spécifique. Le terme « ribozyme » est un mot valise formé à… …   Wikipédia en Français

  • Ribozyme — Modell eines Hammerhead Ribozyms Ribozyme (von Ribonucleinsäure (RNA) und Enzym) sind katalytisch aktive RNA Moleküle, die wie Enzyme chemische Reaktionen katalysieren. Für diese Entdeckung wurden Sidney Altman und Thomas R. Cech 1989 mit dem… …   Deutsch Wikipedia

  • ribozyme — ribozimas statusas T sritis chemija apibrėžtis Ribonukleorūgštis, specifiškai skaidanti fosfodiesterinius ryšius RNR molekulėje. atitikmenys: angl. ribozyme rus. рибозим …   Chemijos terminų aiškinamasis žodynas

  • ribozyme — noun Etymology: ribonucleic acid + enzyme Date: 1982 a molecule of RNA that functions as an enzyme (as by catalyzing the cleavage of other RNA molecules) …   New Collegiate Dictionary

  • ribozyme — RNA with catalytic capacity an enzyme made of nucleic acid not protein. Of particular interest because of the implications for self replicating systems in the earliest stages of the evolution of (terrestrial) life …   Dictionary of molecular biology

  • ribozyme — ribozymal, adj. /ruy beuh zuym /, n. a segment of RNA that can act as a catalyst. [1985 90; RIBO(SOME) + (EN)ZYME] * * * …   Universalium

  • ribozyme — noun a fragment of RNA that can act as an enzyme …   Wiktionary

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