- HIV) and other retroviruses to use their viral RNA as a template to make DNA. Reverse transcriptase is so-named because it reverses the usual transcription of DNA into RNA and lets RNA be transcribed into DNA.
* * *reverse transcriptase n a polymerase esp. of retroviruses that catalyzes the formation of DNA using RNA as a template
* * *an enzyme, found mainly in retrovirus, that catalyses the synthesis of DNA from RNA. It enables the viral RNA to be integrated into the host DNA. Reverse transcriptase inhibitors are antiviral drugs that inhibit this process; they include zidovudine and didanosine, used in the treatment of HIV infection, and lamivudine (Epivir, Zeffix), for treating HIV infection and hepatitis B.
* * *re·verse tran·scrip·tase (re-vursґ tran-skripґtās) RNA-directed DNA polymerase.
Medical dictionary. 2011.
Look at other dictionaries:
Reverse-transcriptase — Transcriptase inverse Transcriptase inverse Général Synonymes EC … Wikipédia en Français
Reverse transcriptase — Transcriptase inverse Transcriptase inverse Général Synonymes EC … Wikipédia en Français
reverse transcriptase — n. an enzyme that makes DNA from RNA, found in retroviruses and widely used in recombinant DNA technology: cf. TRANSCRIPTASE … English World dictionary
reverse transcriptase — reverse transcriptase. См. ревертаза. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
Reverse transcriptase — Protbox Name=Reverse Transcriptase Photo=1HMV.png|250px Caption=3D model of HIV reverse transcriptase HGNCid = Symbol = AltSymbols = Chromosome = Arm = Band = LocusSupplementaryData = Gene= Gene type= Protein length= Molecular weight= Structure=… … Wikipedia
reverse transcriptase — an enzyme, found mainly in retroviruses, that catalyses the synthesis of DNA from RNA. It enables the viral RNA to be integrated into the host DNA. Reverse transcriptase inhibitors are antiviral drugs that inhibit this process; they include… … The new mediacal dictionary
reverse transcriptase — reverse′ tran•scrip′tase [[t]trænˈskrɪp teɪs, teɪz[/t]] n. biochem. a retrovirus enzyme that synthesizes DNA from viral RNA, the reverse of the usual DNA to RNA replication: used in genetic engineering • Etymology: 1970–75 … From formal English to slang
reverse transcriptase — (RT) An RNA dependent DNA polymerase that uses a viral RNA genome as a template to form a DNA copy; this is a reverse of the normal flow of genetic information, which proceeds from DNA to RNA … Dictionary of microbiology
reverse transcriptase — RNA directed DNA polymerase. Enzyme first discovered in retroviruses, that can construct double stranded DNA molecules from the single stranded RNA templates of their genomes. Reverse transcription now appears also to be involved in movement of… … Dictionary of molecular biology
reverse transcriptase — /tran skrip tays, tayz/, Biochem. a retrovirus enzyme that synthesizes DNA from viral RNA, the reverse of the usual DNA to RNA replication: used in genetic engineering to clone genes from RNA strands. [1970 75; TRANSCRIPT + ASE] * * * … Universalium