Recessive, X-linked

A gene on the X chromosome that expresses itself only when there is no different gene present at that locus (spot on the chromosome). For example, Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder. A DMD boy has the DMD gene on his sole X chromosome (and so is said to be hemizygous for DMD). Although it is much rarer, a girl can have DMD (by several different means as, for example, if she has the DMD gene on both her X chromosomes and so is homozygous for DMD).

Medical dictionary. 2011.

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  • Recessive — A trait that is evident only when one copy of the gene for it is inherited from each of the parents. * * * 1. Drawing away; receding. 2. In genetics, denoting a trait due to a particular allele or alleles at a single locus that does not manifest… …   Medical dictionary

  • recessive allele — an allele that is phenotypically expressed only in the homozygous (or hemizygous, for X linked traits) state. Cf. dominant a …   Medical dictionary

  • X-linked recessive chondrodysplasia punctata — Classification and external resources ICD 10 Q77.3 OMIM 302950 …   Wikipedia

  • sex-linked disorder — A genetic defect, usually due to a gene on the unpaired portion of the X chromosome. Recessive X linked alleles are fully expressed in the heterogametic sex because they can have only one copy of the gene. Thus X linked mutant disorders are more… …   Dictionary of molecular biology

  • X-linked adrenal hypoplasia congenita — Classification and external resources OMIM 300200 DiseasesDB 32988 X linked adrenal hypoplasia congenita is a genetic dis …   Wikipedia

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  • X-linked recessive — is a mode of inheritance in which a mutation in a gene on the X chromosome causes the phenotype to be expressed (1) in males (who are necessarily hemizygous for the gene mutation because they have only one X chromosome) and (2) in females who are …   Wikipedia

  • X-linked lymphoproliferative disease — Classification and external resources ICD 10 D82.3 OMIM 308240 300635 …   Wikipedia

  • X-linked dominant — is mode of inheritance in which a gene on the X chromosome is dominant. [ [ X linked Dominant: Incontinentia pigmenti Lucile Packard Children s Hospital] ] Females can be… …   Wikipedia

  • sex-linked — See sex linkage. * * * sex linked adj 1) located in a sex chromosome <a sex linked gene> 2) mediated by a sex linked gene <a sex linked character> * * * adj. describing genes (or the characteristics controlled by them) that are… …   Medical dictionary

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