A very sensitive, specific laboratory test (assay) using radiolabeled (and unlabeled) substances in an immunological (antibody-antigen) reaction.
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An immunologic (immunochemical) procedure that uses the competition between radioisotope-labeled antigen or other substance and unlabeled antigen for antiserums, resulting in quantitation of the unlabeled antigen; any method for detecting or quantitating antigens or antibodies using radiolabeled reactants. Minute quantities of enzymes, hormones, or other substances can be assayed.

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ra·dio·im·mu·no·as·say .rād-ē-ōə-nō-'as-.ā, -im-.yü-, -a-'sā n immunoassay of a substance (as insulin) that has been radiolabeled abbr. RIA
ra·dio·im·mu·no·as·say·able -ə-bəl adj

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a technique using radioactive antibodies as tracer to estimate the levels of natural substances in a blood sample. The antibodies bind to antigens, and the amount of radioactivity trapped is a measure of the amount of the target antigen present. The technique is widely used in the estimation of hormone levels.

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ra·dio·im·mu·no·as·say (ra″de-o-im″u-no-asґa) a highly sensitive and specific assay method that uses the competition between radiolabeled and unlabeled substances in an antigen-antibody reaction to determine the concentration of the unlabeled substance; it can be used to determine antibody concentrations or to determine the concentration of any substance against which specific antibody can be produced. Abbreviated RIA.

Medical dictionary. 2011.

Look at other dictionaries:

  • Radioimmunoassay — (RIA) is a scientific method used to test antigens (for example, hormone levels in the blood) without the need to use a bioassay. It was developed by Rosalyn Yalow and Solomon Aaron Berson in the 1950s. [Yalow RS, Berson SA. Immunoassay of… …   Wikipedia

  • radioimmunoassay — ☆ radioimmunoassay [rā′dē ōim΄yoo nō as′ā, rā′dē ō im΄yoo nōa sā′ ] n. the technique of immunoassay in which radioactive tracers are introduced into the substance to be analyzed …   English World dictionary

  • Radioimmunoassay — Ein Radioimmunoassay (RIA) ist eine Labormethode zur quantitativen Bestimmung kleinster Substanzmengen. Kleine Konzentrationen von Hormonen, Enzymen, Tumorantigenen, Infektionsantigenen, Arzneimitteln und DNA können mit dieser… …   Deutsch Wikipedia

  • radioimmunoassay — noun Date: 1961 immunoassay of a substance that has been radioactively labeled • radioimmunoassayable adjective …   New Collegiate Dictionary

  • radioimmunoassay — (RIA; ra de o im u no as a) A very sensitive assay technique that uses a purified radioisotope labeled antigen or antibody to compete for antibody or antigen with unlabeled standard and samples to determine the concentration of a substance in the …   Dictionary of microbiology

  • radioimmunoassay — Any system for testing antigen antibody reactions in which use is made of radioactive labelling of antigen or antibody to detect the extent of the reaction …   Dictionary of molecular biology

  • radioimmunoassay — /ray dee oh im yeuh noh as ay, a say , i myooh /, n. a test procedure that integrates immunologic and radiolabeling techniques to measure minute quantities of a substance, as a protein, hormone, or drug, in a given sample of body fluid or tissue …   Universalium

  • radioimmunoassay — noun A procedure that uses the binding of a radioactively labeled substance to an antibody in order to analyze minute amounts of biological compounds …   Wiktionary

  • Radioimmunoassay — Ra|di|o|im|mu|no|as|say 〈[ əsɛı] n.; Gen.: s, Pl.: s; Chemie〉 Verfahren der analyt. Immunchemie, bei dem mithilfe eines radioaktiv markierten Antigens od. Antikörpers eine Immunreaktion erzeugt wird, die Schlüsse auf die Qualität u. Quantität der …   Lexikalische Deutsches Wörterbuch

  • radioimmunoassay — noun Medicine a technique for measuring antibody levels using radioactively labelled antigens …   English new terms dictionary

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