* * *diagnostic procedures carried out on pregnant women in order to discover genetic or other abnormalities in the developing fetus. Ultrasound scanning (see ultrasonography) remains the cornerstone of prenatal diagnosis. Other procedures include estimation of the level of alpha-fetoprotein in the mother's serum and the amniotic fluid; chromosome and enzyme analysis of fetal cells obtained by amniocentesis or, at an earlier stage of pregnancy, by chorionic villus sampling (CVS); and examination of fetal blood obtained by fetoscopy or cordocentesis. If the results indicate that the child is likely or certain to be born with severe malformation or abnormality, the possibility of abortion is discussed by the doctors involved with the parents.Until recently, prenatal genetic diagnosis was dependent on CVS and amniocentesis, but it may now be extended to the earliest stages of embryonic development, before implantation occurs (preimplantation genetic diagnosis; PGD). Access to these early embryos requires the removal and in vitro fertilization of egg cells: three days after fertilization one or two cells are aspirated from the six- to eight-cell embryo; alternatively, tissue is removed from an embryo at five or six days, when it has reached the blastocyst stage. Isolated cells can then be genetically analysed, using the polymerase chain reaction amplification technique to produce enough DNA for genetic diagnosis. Even before pregnancy, this technique can be used to enable a prospective mother to be identified as the carrier of a gene defect, by means of the mouthwash test. When a defect is detected, genetic counselling is offered.
Medical dictionary. 2011.
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Prenatal diagnosis — Prenatal testing is testing for diseases or conditions in a fetus or embryo before it is born. The aim is to detect birth defects such as neural tube defects, Down syndrome, chromosome abnormalities, genetic diseases and other conditions. It can… … Wikipedia
prenatal diagnosis — prenatal diagnosis. См. пренатальная диагностика. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
prenatal diagnosis — antenatal diagnosis diagnostic procedures carried out on pregnant women in order to detect the presence of genetic or other abnormalities in the developing fetus. Ultrasound scanning (see ultrasonography) remains the cornerstone of prenatal… … The new mediacal dictionary
prenatal diagnosis — diagnosis of disease or physiological problems in a fetus while it is still inside the mother s uterus … English contemporary dictionary
prenatal diagnosis — noun any of the diagnostic procedures used to determine whether a fetus has a genetic abnormality • Hypernyms: ↑diagnostic procedure, ↑diagnostic technique • Hyponyms: ↑sonography, ↑ultrasonography, ↑echography, ↑ultrasound, ↑ … Useful english dictionary
Диагностика Пренатальная (Prenatal Diagnosis), Диагностика Антенатальная (Antenatal Diagnosis) — диагностические процедуры, выполняемые в ходе обследования беременной женщины для выявления генетических или каких либо иных аномалий в развитии плода. Основой пренатальной диагностики является ультразвуковое сканирование (см. Ультрасонография).… … Медицинские термины
Diagnosis of fetal aneuploidy — Fetal aneuploidy is not as common as other birth defects, affecting 9 in 1000 births and increasing with maternal age. Amniocentesis and chorionic villus sampling have historically been two of the most popular methods used to detect fetal… … Wikipedia
diagnosis — /duy euhg noh sis/, n., pl. diagnoses / seez/. 1. Med. a. the process of determining by examination the nature and circumstances of a diseased condition. b. the decision reached from such an examination. Abbr.: Dx 2. Biol. scientific… … Universalium
Prenatal — Occurring or existing before birth. Prenatal care is the regular health care women should receive during pregnancy from an obstetrician or midwife. Prenatal development is the growth and development of a single celled zygote formed by the… … Medical dictionary
diagnosis — The determination of the nature of a disease, injury, or congenital defect. SYN: diacrisis. [G. d., a deciding] antenatal d. SYN: prenatal d.. clinical d. a d. made from a study of the signs and symptoms of a d … Medical dictionary