Pick disease

A form of dementia characterized by a slowly progressive deterioration of social skills and changes in personality leading to impairment of intellect, memory, and language. Dementia can be defined as a loss of intellectual abilities such as memory capacity, severe enough to interfere with social or occupational functioning. The criteria for the diagnosis of dementia include impairment of attention, orientation, memory, judgment, language, motor and spatial skills, and function. By definition,

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1. [Arnold Pick] a rare progressive degenerative disease of the brain, similar in clinical manifestations and course to Alzheimer disease but having a distinctive histopathology; cortical atrophy is confined to the frontal and temporal lobes; degenerating neurons contain globular intracytoplasmic filamentous inclusions (Pick bodies). Called also circumscribed cerebral atrophy. 2. [Ludwig Pick] Niemann-Pick d.

Medical dictionary. 2011.

Look at other dictionaries:

  • Pick disease — ▪ pathology       form of premature dementia caused by atrophy of the frontal and temporal lobes of the brain. It resembles Alzheimer disease but is much less common. Pick disease is characterized by a progressive deterioration of intellect,… …   Universalium

  • Niemann-Pick disease, type C — Classification and external resources ICD 10 E75.2 (ILDS E75.230) ICD 9 272.7 …   Wikipedia

  • Niemann–Pick disease — Niemann Pick disease Classification and external resources ICD 10 E75.2 (ILDS E75.230) ICD 9 272.7 …   Wikipedia

  • Niemann-Pick disease — Infobox Disease Name = Niemann Pick disease Caption = DiseasesDB = ICD10 = ICD10|E|75|2|e|70 (ILDS E75.230) ICD9 = ICD9|272.7 ICDO = OMIM = MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = D009542 Niemann Pick Disease is one of a group of… …   Wikipedia

  • Niemann-Pick disease, SMPD1-associated — Classification and external resources ICD 10 E75.2 (ILDS E75.230) ICD 9 272.7 …   Wikipedia

  • Niemann-Pick disease — A disorder of the metabolism of a lipid (fat) called sphingomyelin that usually causes the progressive development of enlargement of the liver and spleen (hepatosplenomegaly), swollen glands (lymphadenopathy), anemia and mental and physical… …   Medical dictionary

  • Nieman-Pick disease — Nieman Pick disease. См. фосфатидный липидоз. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Niemann-Pick disease — noun a disorder of lipid metabolism that is inherited as an autosomal recessive trait • Hypernyms: ↑inborn error of metabolism, ↑lipidosis, ↑autosomal recessive disease, ↑autosomal recessive defect * * * ˈnēˌmänˈpik noun Usage: usually… …   Useful english dictionary

  • Niemann-Pick disease — /nee meuhn pik /, Pathol. a rare, hereditary lipid storage disease, occurring primarily among Ashkenazic Jews, in which abnormal lipid metabolism results in enlargement of the liver, spleen, and lymph nodes, and in progressive mental and physical …   Universalium

  • Niemann-Pick disease — an inherited (autosomal recessive) disorder of lipid metabolism due to a defect in the enzyme sphingomyelinase and resulting in accumulation of sphingomyelin and other phospholipids in the bone marrow, brain, liver, and spleen. Patients present… …   The new mediacal dictionary

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