Phage

Short for bacteriophage, a virus that lives within a bacteria. Bacteriophages have been very important and heuristic in bacterial and molecular genetics. Phages were studied by (among others) Alfred Hershey, Max Delbruck and Salvador Luria who discovered that viruses could exchange genetic material. Hershey and a graduate student Martha Chase at the Cold Spring Harbor Laboratory found that nucleic acid alone could cause viral replication and transmit genetic information. The classic Hershey and Chase experiment provided some of the key proof that genes were, indeed, made of DNA. The "phage group" (Hershey, Delbruck and Luria) went on to share the 1969 Nobel Prize for Physiology or Medicine for their discoveries concerning "the replication mechanism and the genetic structure of viruses." Delbruck died in 1981, Luria in 1991, and Hershey in 1997. The famous "phage group" is thus gone but their legacy and that of the phages lives on.
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- β p. SYN: β corynebacteriophage.
- defective p. SYN: defective bacteriophage.
- Lambda p. a bacteriophage used extensively in experimental systems.

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phage 'fājalso 'fäzh n BACTERIOPHAGE

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n.

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(fāj) bacteriophage.

Medical dictionary. 2011.

Look at other dictionaries:

  • -phage — phage, phagie, phagique ♦ Éléments, du gr. phagos et phagia, de phagein « manger » (⇒ vore) : aérophagie; anthropophage, hippophagique; nécrophage. phag(o) , phage, phagie, phagique éléments, du gr. phagein, manger . ⇒ PHAGE, PHAGIE, PHAGIQUE,… …   Encyclopédie Universelle

  • Phage T4 — Phage T4 …   Wikipédia en Français

  • phage — [ faʒ ] n. m. • 1955; aphérèse de bactériophage ♦ Biol. Bactériophage. ● phage nom masculin Synonyme de bactériophage. ● phage (synonymes) nom masculin Synonymes : bactériophage phage n. m. MICROB Bactériophage, vir …   Encyclopédie Universelle

  • phage λ — phage λ. = lambda phage (см.). (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • phage — phage. См. фаги. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • phage λ — phage λ. См. фаг лямбда. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • phage — phage. См. мю фаг. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • phage — phage. = bacteriophage (см.). (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • phage — 1925 as an abbreviated form of BACTERIOPHAGE (Cf. bacteriophage) …   Etymology dictionary

  • -phage — [fāj] [< Gr phagein: see PHAGOUS] combining form forming nouns one that eats or destroys (something specified) [bacteriophage] …   English World dictionary

  • phage — [fāj] n. short for BACTERIOPHAGE …   English World dictionary

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