Nucleic acid hybridization
- FISH) analysis.
* * *formation of a partially or wholly complementary DNA-RNA, DNA-DNA, or RNA-RNA duplex by association of single-stranded nucleic acids, sometimes specifically from different sources; used as the basis of a wide variety of techniques for analysis of nucleic acids and detection and isolation of specific sequences.
Medical dictionary. 2011.
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Nucleic acid hybridization — Hybridization is the process, discovered by Alexander Rich, of combining complementary, single stranded nucleic acids into a single molecule. Nucleotides will bind to their complement under normal conditions, so two perfectly complementary… … Wikipedia
nucleic acid hybridization — (nu kle ik) The process of forming a hybrid double stranded DNA molecule using a heated mixture of single stranded DNAs from two different sources; if the sequences are fairly complementary, stable hybrids will form … Dictionary of microbiology
Nucleic acid double helix — Double helix redirects here. For other uses, see Double helix (disambiguation). Two complementary regions of nucleic acid molecules will bind and form a double helical structure held together by base pairs. In molecular biology, the term double… … Wikipedia
Nucleic acid secondary structure — The secondary structure of a nucleic acid molecule refers to the basepairing interactions within a single molecule or set of interacting molecules, and can be represented as a list of bases which are paired in a nucleic acid molecule. The… … Wikipedia
Hybridization, nucleic acid — A laboratory technique in which single stranded nucleic acids (DNA or RNA) are allowed to interact so that complexes called hybrids are formed by molecules with similar, complementary sequences. Through nucleic acid hybridization, the degree of… … Medical dictionary
Nucleic acid thermodynamics — is the study of the thermodynamics of nucleic acid molecules, or how temperature affects nucleic acid structure. For multiple copies of DNA molecules, the melting temperature (Tm) is defined as the temperature at which half of the DNA strands are … Wikipedia
Nucleic acid design — can be used to create nucleic acid complexes with complicated secondary structures such as this four arm junction. These four strands associate into this structure because it maximizes the number of correct base pairs, with A s matched to T s and … Wikipedia
nucleic acid — /nooh klee ik, klay , nyooh /, Biochem. any of a group of long, linear macromolecules, either DNA or various types of RNA, that carry genetic information directing all cellular functions: composed of linked nucleotides. [1890 95; NUCLE(US) + IC;… … Universalium
Nucleic acid analogues — Not to be confused with degenerate bases. For phosphoramidite synthesis of nucleic acids, see Oligonucleotide synthesis. RNA with its nucleobases to the left and DNA to the right. Nucleic acid analogues are compounds structurally similar (analog) … Wikipedia
Nucleic acid structure prediction — This article is about the computational prediction of nucleic acid structure. For experimental methods, see Nucleic acid structure determination. Nucleic acid structure prediction is a computational method to determine nucleic acid secondary and… … Wikipedia