DNASE

deoxyribo-nuclease

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DN·ase (')dē-'en-.ās, -.āz also DNA·ase (.)dē-.en-'ā-.ās, -.āz n DEOXYRIBONUCLEASE

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n.
an enzyme that catalyses the cleavage of DNA. A genetically engineered form, recombinant human DNAse (dornase alfa), is used in the treatment of cystic fibrosis to reduce the viscosity of the sticky secretions in the lungs. Administered by inhalation via a jet nebulizer, it appears to hydrolyse extracellular DNA that accumulates with other neutrophil debris in the airways. Trade name: Pulmozyme.

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deoxyribonuclease.

Medical dictionary. 2011.

Look at other dictionaries:

  • DNase — (d[=e] [e^]n*[=a]s ), DNAase DNAase (d[=e] [e^]n*[=a] [=a]s) n. (Biochem.) any of numerous enzymes that catalyze the breakdown of DNA into oligonucleotides or mononucleotides. [PJC] …   The Collaborative International Dictionary of English

  • Dnase — Deoxyribonuclease Short Dictionary of (mostly American) Legal Terms and Abbreviations …   Law dictionary

  • DNase — [Kurzw. aus ↑ DNA u. ↑ ase], die; , n: svw. ↑ Desoxyribonuklease …   Universal-Lexikon

  • DNase — Desoxyribonuklease Arzneistoffangaben ATC Code B06 …   Deutsch Wikipedia

  • DNAse — Désoxyribonucléase La désoxyribonucléase, ou DNAse est une enzyme catalysant les acides désoxyribonucléiques en nucléotides ou polynucléotides. Elle hydrolyse les liaisons phosphodiester. Prenons le cas de la DNase I : cette endonucléase… …   Wikipédia en Français

  • DNAse — n. an enzyme that catalyses the cleavage of DNA. A genetically engineered form, recombinant human DNAse (dornase alfa), is used in the treatment of cystic fibrosis to reduce the viscosity of the sticky secretions in the lungs. Administered by… …   The new mediacal dictionary

  • DNAse — Abbreviation for deoxyribonuclease Any enzyme that catalyses the cleavage of DNA phosphodiester bonds. DNAse I is a digestive endonuclease secreted by the pancreas, that degrades DNA into shorter fragments. Many other endonucleases and… …   Glossary of Biotechnology

  • DNase — also DNAase noun Date: circa 1956 an enzyme that hydrolyzes DNA to nucleotides called also deoxyribonuclease …   New Collegiate Dictionary

  • DNase — /dee en ays, ayz/ deoxyribonuclease: any of several enzymes that break down the double stranded or single stranded DNA molecule into its component nucleotides. Also, DNAase. * * * …   Universalium

  • DNase — noun deoxyribonuclease …   Wiktionary

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