- Antithyroid drug
- A drug directed against the thyroid gland. The antithyroid drugs include carbimazole, methimazole, and propylthiouracil (PTU). These drugs are used to treat hyperthyroidism (overactivity of the thyroid gland) in order to reduce the excessive thyroid activity before surgery and to treat and maintain patients not having surgery. Carbimazole, its active metabolite methimazole, and propylthiouracil all act by inhibiting the enzyme thyroid peroxidase and in that way they block the synthesis (the production) of thyroid hormone. About 30 to 40% of patients treated with an antithyroid drug remain euthyroid (with normal levels of thyroid hormone) 10 years after the discontinuation of antithyroid drug therapy, which means that the Graves disease (the most common cause of hyperthyroidism) is in remission. A common problem with antithyroid drugs is undershooting or overshooting causing persistent hyperthyroidism or hypothyroidism. A rare complication of antithyroid therapy is agranulocytosis (decrease in white blood cells) which calls for immediate discontinuation of the drug.
Medical dictionary. 2011.
Look at other dictionaries:
Drug, antithyroid — A drug directed against the thyroid gland. The antithyroid drugs include carbimazole, methimazole, and propylthiouracil (PTU). These drugs are used to treat hyperthyroidism (overactivity of the thyroid gland) in order to reduce the excessive… … Medical dictionary
Drug — For other uses, see Drug (disambiguation). Coffee is the most widely used psychoactive drug beverage in the w … Wikipedia
Pharmaceutical drug — Medication redirects here. For other uses, see Medication (disambiguation). Medicines redirects here. For other uses, see Medicine (disambiguation). A pharmaceutical drug, also referred to as medicine, medication or medicament, can be loosely… … Wikipedia
Psychoactive drug — An assortment of psychoactive drugs A psychoactive drug, psychopharmaceutical, or psychotropic is a chemical substance that crosses the blood–brain barrier and acts primarily upon the central nervous system where it affects brain function,… … Wikipedia
Non-steroidal anti-inflammatory drug — Coated 200 mg Ibuprofen tablets, a common NSAID Nonsteroidal anti inflammatory drugs, usually abbreviated to NSAIDs or NAIDs, but also referred to as nonsteroidal anti inflammatory agents/analgesics (NSAIAs) or nonsteroidal Anti inflammatory… … Wikipedia
Disease-modifying antirheumatic drug — Methotrexate Hydroxychloro … Wikipedia
Thrombolytic drug — Thrombolytic drugs are used in medicine to dissolve blood clots in a procedure termed thrombolysis. They limit the damage caused by the blockage of the blood vessel. Contents 1 Uses 2 Members 3 Side effects … Wikipedia
Graves' disease — Classification and external resources Photo showing the classic finding of proptosis and lid retraction in Graves disease ICD 10 … Wikipedia
endocrine system, human — ▪ anatomy Introduction group of ductless glands (gland) that regulate body processes by secreting chemical substances called hormones (hormone). Hormones act on nearby tissues or are carried in the bloodstream to act on specific target organs… … Universalium
Methimazole — Not to be confused with metamizole . Methimazole Systematic (IUPAC) name 1 methyl 3H imidazole 2 thione Clinical data … Wikipedia