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* * *an·ti·psy·chot·ic .ant-i-sī-'kät-ik, .an-.tī- adj of, being, or involving the use of an antipsychotic <\antipsychotic drugs>antipsychotic n any of the powerful tranquilizers (as the phenothiazines or butyrophenones) used esp. to treat psychosis and believed to act by blocking dopamine nervous receptors called also neuroleptic
* * *adj.describing a group of drugs used to treat severe mental disorders (psychoses), including schizophrenia and mania; some are administered in small doses to relieve anxiety. Formerly known as major tranquillizers, antipsychotic drugs include the phenothiazines (e.g. chlorpromazine), butyrophenone (e.g. haloperidol), and thioxanthenes (e.g. flupentixol). The atypical antipsychotics are a group of more recently developed drugs that may be helpful in those who do not respond to treatment with other antipsychotics. They include clozapine, risperidone, olanzapine (Zyprexa), and quietapine (Seroquel). Side-effects of many antipsychotics at high doses include abnormal involuntary movements.
* * *an·ti·psy·chot·ic (an″te-) (an″ti-si-kotґik) 1. effective in treatment of psychosis. 2. an agent for treating psychosis. Antipsychotics are a chemically diverse group (including phenothiazines, thioxanthenes, butyrophenones, dibenzoxazepines, dibenzodiazepines, dihydroindolones, and diphenylbutylpiperidines), although they are pharmacologically similar; used to treat schizophrenic, paranoid, schizoaffective, and other psychotic disorders; acute delirium and dementia and manic episodes; to control the movement disorders associated with Huntington chorea, Gilles de la Tourette syndrome, and ballismus; and to treat intractable hiccups and severe nausea and vomiting. Antipsychotic agents bind to dopamine, histamine, muscarinic cholinergic, α-adrenergic, and serotonin receptors. Blockade of dopaminergic transmission in various areas is thought to be responsible for their major effects: antipsychotic action by blockade in the mesolimbic and mesocortical areas; extrapyramidal side effects (dystonia, akathisia, parkinsonism, and tardive dyskinesia) by blockade in the basal ganglia; and antiemetic effects by blockade in the chemoreceptor trigger zone of the medulla. Sedation and autonomic side effects (orthostatic hypotension, blurred vision, dry mouth, nasal congestion, and constipation) are caused by blockade of histamine, cholinergic, and adrenergic receptors. Called also neuroleptic.
Medical dictionary. 2011.
Look at other dictionaries:
antipsychotic — [an΄tī sī kät′ik; an΄tēsī kät′ik, an΄tīsī kät′ik] adj. tranquilizing; neuroleptic n. an antipsychotic drug … English World dictionary
Antipsychotic — Advertisement for Thorazine (chlorpromazine) from the 1950s An antipsychotic (or neuroleptic) is a tranquilizing psychiatric medication primarily used to manage psychosis (including delusions or hallucinations, as well as disordered tho … Wikipedia
antipsychotic — adj. describing a group of drugs used to treat severe mental disorders (psychoses), including schizophrenia and mania; some are administered in small doses to relieve anxiety. Formerly known as major tranquillizers, antipsychotic drugs include… … The new mediacal dictionary
antipsychotic — noun tranquilizer used to treat psychotic conditions when a calming effect is desired • Syn: ↑major tranquilizer, ↑major tranquillizer, ↑major tranquilliser, ↑antipsychotic drug, ↑antipsychotic agent, ↑neuroleptic drug, ↑neuroleptic agent, ↑ … Useful english dictionary
antipsychotic — noun Date: 1966 any of the powerful tranquilizers (as the phenothiazines and butyrophenones) used especially to treat psychosis and believed to act by blocking dopamine nervous receptors called also neuroleptic • antipsychotic adjective … New Collegiate Dictionary
antipsychotic — adjective used to treat psychotic disorders. noun an antipsychotic drug … English new terms dictionary
antipsychotic — an•ti•psy•chot•ic [[t]ˌæn ti saɪˈkɒt ɪk, ˌæn taɪ [/t]] adj. 1) pha of or pertaining to any of various drugs used in the treatment of psychosis, esp. schizophrenia, and severe states of mania, depression, or paranoia 2) pha Also called neuroleptic … From formal English to slang
antipsychotic — /an tee suy kot ik, an tuy /, Pharm. adj. 1. of or pertaining to any of various substances used in the treatment of psychosis, esp. schizophrenia, and acute or severe states of mania, depression, or paranoia. n. 2. Also called major tranquilizer … Universalium
antipsychotic — 1. adjective Preventing or counteracting psychosis. Syn: neuroleptic 2. noun Any of a group of drugs used to treat psychosis a mental disorder marked by a deranged personality and a distorted view of reality. Syn … Wiktionary
antipsychotic — adj. against psychotic episodes … English contemporary dictionary