- homogeneous, or diffuse; speckled; nucleolar; and peripheral or rim. While these patterns are not specific for any one illness, certain illnesses can more frequently be associated with one pattern or another. For example, the nucleolar pattern is more commonly seen in the disease scleroderma. The speckled pattern is seen in many conditions and in persons who do not have any autoimmune disease.
Medical dictionary. 2011.
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Antinuclear antibody test — A test for unusual antibodies that are directed against structures within the nucleus of the cell. Antinuclear antibodies (ANAs) indicate the possible presence of autoimmunity. The fluorescent antinuclear antibody test (FANA) was designed by… … Medical dictionary
Antibody, antinuclear — An unusual antibody that is directed against structures within the nucleus of the cell. Antinuclear antibodies (ANAs) are found in patients whose immune system is predisposed to cause inflammation against their own body tissues. Antibodies that… … Medical dictionary
antinuclear — Having an affinity for or reacting with the cell nucleus. * * * an·ti·nu·cle·ar n(y)ü klē ər adj being antibodies or autoantibodies that react with components and esp. DNA of cell nuclei and that tend to occur frequently in connective tissue… … Medical dictionary
antinuclear antibodies — (ANA) antibodies directed against nuclear antigens; ones against a variety of different antigens are almost invariably found in systemic lupus erythematosus and are frequently found in rheumatoid arthritis, scleroderma (systemic sclerosis),… … Medical dictionary
antibody — An immunoglobulin molecule produced by B lymphoid cells with a specific amino acid sequence evoked in humans or other animals by an antigen (immunogen). These molecules are characterized by reacting specifically with the antigen in some… … Medical dictionary
antinuclear factor — (ANF) see under antibody … Medical dictionary
Anti-nuclear antibody — Anti nuclear antibodies (ANAs, also known as anti nuclear factor or ANF ) are antibodies directed against contents of the cell nucleus. [MeshName|Antinuclear+Antibody] They are present in higher than normal numbers in autoimmune disease. The ANA… … Wikipedia
anti-dsDNA antibody — a type of antinuclear antibody specific for double stranded DNA, found in the serum of patients with systemic lupus erythematosus … Medical dictionary
antiâ€“SS-A antibody — an antinuclear antibody that occurs in SjÑ†gren syndrome and systemic lupus erythematosus. Called also anti Ro a … Medical dictionary
antiâ€“SS-B antibody — an antinuclear antibody that occurs in SjÑ†gren syndrome and systemic lupus erythematosus. Called also anti La a … Medical dictionary