zidovudine

A thymidine analog that is an inhibitor of in vitro replication of HIV virus, the causative agent of AIDS and ARC, and is used in the management of these diseases. SYN: azidothymidine.

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zi·do·vu·dine zī-'dō-v(y)ü-.dēn n AZT

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(AZT)
n.
an antiviral drug used in the treatment of AIDS and HIV infection. The drug slows the growth of HIV infection in the body, but is not curative. It is administered by mouth and intravenously; the most common side-effects are nausea, headache, and insomnia, and it may damage the blood-forming tissues of the bone marrow. Trade name: Retrovir.

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zi·do·vu·dine (zi-doґvu-dēn) [USP] a synthetic nucleoside analogue, of thymidine, that inhibits replication of some retroviruses, including the human immunodeficiency virus (HIV); used in the management of HIV infection and acquired immunodeficiency syndrome (AIDS), administered orally or intravenously.

Medical dictionary. 2011.

Look at other dictionaries:

  • zidovudine — [ zidɔvydin ] n. f. • 1987; mot angl. , de (a)zido (deoxythymi)dine ♦ Méd. Produit antiviral utilisé dans le traitement du sida, couramment nommé AZT. ● zidovudine nom féminin Médicament antiviral actif sur les rétrovirus, en particulier sur le V …   Encyclopédie Universelle

  • zidovudine — [zī dō′vyo͞o dēn΄] n. an antiviral drug used in the treatment of AIDS; AZT …   English World dictionary

  • Zidovudine — AZT redirects here. For other uses, see AZT (disambiguation). Zidovudine Systematic (IUPAC) name …   Wikipedia

  • Zidovudine — Pour les articles homonymes, voir AZT. Zidovudine …   Wikipédia en Français

  • Zidovudine — Strukturformel Allgemeines Freiname Zidovudin Andere Namen Azidot …   Deutsch Wikipedia

  • zidovudine — azidothymidine azidothymidine n. 1. 1 an antiviral drug, ({C10H13N5O4}) used in the treatment of AIDS. It has the generic name of {zidovudine}. Note: an analog of thymidine, it inhibits the replication of the viral chromosome. Syn: AZT,… …   The Collaborative International Dictionary of English

  • Zidovudine — ЗИДОВУДИН ( Zidovudine ). 1 (3 1 Азидо 2 1 дезоксирибозил) тимидин. Синонимы: Ретровир, Retrovir. Новый противовирусный препарат, ингибирующий репликацию ретровирусов, включая вирус иммунодефицита человека (ВИЧ). Предложен для применения в… …   Словарь медицинских препаратов

  • zidovudine — noun Etymology: by shortening & alteration from azidothymidine Date: 1987 AZT …   New Collegiate Dictionary

  • zidovudine — (= AZT; azido deoxythymidine; retrovir) Thymidine analogue; phosphorylated form acts as an inhibitor of viral reverse transcriptase. Used in HIV treatment …   Dictionary of molecular biology

  • zidovudine — /zuy doh vyooh deen /, n. Pharm. the international generic term for azidothymidine. Cf. AZT. * * * …   Universalium

  • zidovudine — noun A nucleoside analog reverse transcriptase inhibitor, a type of antiretroviral drug, the first approved treatment for HIV. Syn: azidothymidine …   Wiktionary

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