Mast cell

A connective tissue cell whose normal function is unknown, the mast cell is frequently injured during allergic reactions, releasing strong chemicals including histamine into the tissues and blood that are very irritating and cause itching, swelling, and fluid leaking from cells. These allergic chemicals can also cause muscle spasm and lead to lung and throat tightening as is found in asthma and loss of voice.

* * *

mast cell 'mast- n a granulocyte that occurs esp. in connective tissue and has basophilic granules containing substances (as histamine and heparin) which mediate allergic reactions

* * *

a large cell in connective tissue with many coarse cytoplasmic granules. These granules contain the chemicals heparin, histamine, and serotonin, which are released during inflammation and allergic responses.

* * *

a type of connective tissue cell whose specific physiologic function remains unknown; it can elaborate basophilic, metachromatic, cytoplasmic granules that contain histamine and heparin in humans and serotonin in species such as the rat and mouse. Called also mastocyte and labrocyte.

Medical dictionary. 2011.

Look at other dictionaries:

  • Mast cell — Mast cells Latin mastocytus Code TH …   Wikipedia

  • mast cell — mast′ cell n. hic (lab cbl) a large granular cell, common in connective tissue, that produces heparin, histamine, and serotonin • Etymology: 1885–90; partial trans. of G Mastzelle=Mast mast II+Zelle cell …   From formal English to slang

  • mast cell — n. [< Ger mastzelle < mast, food (see MAST2) + zelle, cell < OHG cella < L: see CELL] a cell containing large, basophilic granules, found in connective and other body tissues …   English World dictionary

  • mast cell — noun a large connective tissue cell that contains histamine and heparin and serotonin which are released in allergic reactions or in response to injury or inflammation • Syn: ↑mastocyte, ↑labrocyte • Hypernyms: ↑somatic cell, ↑vegetative cell •… …   Useful english dictionary

  • mast cell — /ˈmast sɛl/ (say mahst sel) noun a cell found in the connective tissues of vertebrates, and thought to produce histamines. {German Mastzelle, from Mast mast2 + Zelle cell1} …   Australian English dictionary

  • mast cell — Biol. a large granular cell, common in connective tissue, that produces heparin, histamine, and serotonin. [1885 90; partial trans. of G Mastzelle, equiv. to Mast fattening of animals for slaughter, MAST2 + Zelle cell] * * * ▪ biology… …   Universalium

  • mast cell — Resident cell of connective tissue that contains many granules rich in histamine and heparan sulphate. Release of histamine from mast cells is responsible for the immediate reddening of the skin in a weal and flare response. Very similar to… …   Dictionary of molecular biology

  • mast cell — noun Etymology: part translation of German Mastzelle, from Mast food, mast (from Old High German) + Zelle cell Date: circa 1890 a granulocyte that occurs especially in connective tissue and has basophilic granules containing substances (as… …   New Collegiate Dictionary

  • mast cell — noun a cell found in connective tissue and releasing histamine and other substances during inflammatory and allergic reactions. Origin C19: mast from Ger. Mast fattening, feeding …   English new terms dictionary

  • mast cell — A bone marrow derived cell present in a variety of tissues that resembles peripheral blood borne basophils and contains an Fc receptor for IgE. It undergoes IgE mediated degranulation …   Dictionary of microbiology

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.