vincristine sulfate

A dimeric alkaloid obtained from Vinca rosea; its antineoplastic activity is similar to that of vinblastine, but no cross-resistance develops between these two agents, and it is more useful than vinblastine in lymphocytic lymphosarcoma and acute leukemia. SYN: leurocristine.

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vin·cris·tine sul·fate (vin-krisґtēn) [USP] the sulfate salt of a vinca alkaloid, used as an antineoplastic agent, primarily as a component of combination chemotherapy regimens for Hodgkin disease, acute lymphoblastic leukemia, and non-Hodgkin lymphomas, as well as in the treatment of other neoplastic disorders including Wilms tumor, neuroblastoma, AIDS-associated Kaposi sarcoma, and rhabdomyosarcoma. Administered intravenously.

Medical dictionary. 2011.

Look at other dictionaries:

  • vincristine — ☆ vincristine [vin kris′tēn, vin kris′tin ] n. [< L vinca, periwinkle (prob. < vincere: see VINCULUM) + crista, crest + INE3] an alkaloid, C46H56N4O10·H2SO4, obtained from the leaves of a periwinkle ( Vinca rosea) and used as a drug in the… …   English World dictionary

  • vincristine — ● vincristine nom féminin Alcaloïde de la pervenche d Amérique (Vinca rosea) utilisé, à l état de sulfate notamment, dans le traitement des leucémies aiguës …   Encyclopédie Universelle

  • vincristine — noun Etymology: vinca + Latin crista crest + English 2 ine more at crest Date: circa 1962 an alkaloid C46H56N4O10 from the rosy periwinkle used especially in the form of its sulfate to treat some human neoplastic diseases (as acute leukemia) …   New Collegiate Dictionary

  • vincristine — vin·cris·tine ( )vin kris .tēn n an alkaloid that is obtained from the rosy periwinkle and that is used esp. in the form of its sulfate C46H56N4O10·H2SO4 to treat some human neoplastic diseases (as acute leukemia) called also leurocristine see… …   Medical dictionary

  • vinblastine sulfate — A dimeric alkaloid obtained from Vinca rosea. It arrests mitosis in metaphase (although vincristine is more active in this respect) and exhibits greater antimetabolic activity than does vincristine; used in the treatment of Hodgkin disease,… …   Medical dictionary

  • List of IARC Group 3 carcinogens — Substances, mixtures and exposure circumstances in this list have been classified by the IARC as Group 3: The agent (mixture or exposure circumstance) is not classifiable as to its carcinogenicity to humans. This category is used most commonly… …   Wikipedia

  • leurocristine — SYN: vincristine sulfate. * * * leu·ro·cris·tine .lu̇r ō kris .tēn n VINCRISTINE …   Medical dictionary

  • POMP — Abbreviation for Purinethol (6 mercaptopurine), Oncovin (vincristine sulfate), methotrexate, and prednisone, a cancer chemotherapy regimen. * * * phase offset multiplanar [pulse sequence in magnetic resonance imaging]; principal outer material… …   Medical dictionary

  • Oncovin — On·co·vin äŋ kō .vin n a preparation of vincristine formerly a U.S. registered trademark * * * On·co·vin (ongґko vin) trademark for a preparation of vincristine sulfate …   Medical dictionary

  • Vincristin — Strukturformel Allgemeines Freiname Vincristin Andere Namen …   Deutsch Wikipedia

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