vaccinia

An infection, primarily local and limited to the site of inoculation, induced in humans by inoculation with the v. virus, type species in the genus Orthopoxvirus (family Poxviridae) in order to confer resistance to smallpox. On about the third day after this vaccination, papules form at the site of inoculation which become transformed into umbilicated vesicles and later pustules; they then dry up, and the scab falls off on about the 21st day, leaving a pitted scar; in some cases there are more or less marked constitutional disturbances. Because of the global elimination of smallpox, routine vaccination is not now practiced. SYN: primary reaction, vaccina, variola vaccine, variola v., variola v.. [L. vaccinus, relating to a cow, fr. vacca, a cow]
- v. gangrenosa SYN: progressive v..
- generalized v. secondary lesions of the skin following vaccination that may occur in subjects with previously healthy skin but are more common in the case of traumatized skin, especially in the case of eczema (eczema vaccinatum). In the latter instance, generalized v. may result from mere contact with a vaccinated person. Secondary vaccinial lesions may also occur following transfer of virus from the vaccination to another site by means of the fingers.
- progressive v. a severe or even fatal form of v. occurring chiefly in subjects with an immunologic deficiency or dyscrasia and characterized by progressive enlargement of the initial and also of secondary lesions. SYN: v. gangrenosa.
- variola v. SYN: v..

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vac·cin·ia vak-'sin-ē-ə n
1 a) COWPOX
b) a reaction to smallpox vaccine prepared from live vaccinia virus that may involve a rash, fever, headache, and body pain
2) a poxvirus of the genus Orthopoxvirus (species Vaccinia virus) that differs from but is closely related to the viruses causing smallpox and cowpox and that includes a strain of uncertain natural origin used in making vaccines against smallpox called also vaccinia virus
vac·cin·i·al -ē-əl adj

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n.

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vac·cin·ia (vak-sinґe-ə) [L., from vacca cow] the cutaneous and sometimes systemic reactions associated with vaccination with smallpox vaccine. Cf. cowpox and paravaccinia. vaccinial adj

Medical dictionary. 2011.

Look at other dictionaries:

  • vaccinia — f. inmun. Reacción cutánea o generalizada que puede ocurrir tras la vacunación contra la viruela. Medical Dictionary. 2011. vaccinia …   Diccionario médico

  • Vaccinia — Vac*cin i*a, n. [NL. See {Vaccine}.] (Med.) Cowpox; vaccina. See {Cowpox}. [1913 Webster] …   The Collaborative International Dictionary of English

  • Vaccinĭa — (lat., Vaccine), die Kuhpocken. V. notha (V. spuria, Vaccinella), falsche, unechte Kuhpocken, s.u. Kuhpocken S. 881. Vaccinella (Vaccinetta, Vaccinois, modificirte Kuhpocke), entstehen bei solchen, welche bereits die natürlichen Pocken od. die… …   Pierer's Universal-Lexikon

  • vaccinia — [vak sin′ē ə] n. [ModL < L vaccinus: see VACCINE] COWPOX vaccinial adj …   English World dictionary

  • Vaccinia — Taxobox | color=violet name = Vaccinia virus image caption = A TEM micrograph of Vaccinia virus virions. virus group = i familia = Poxviridae genus = Orthopoxvirus species = Vaccinia virus DiseaseDisorder infobox Name = Vaccinia ICD10 = B08.0… …   Wikipedia

  • vaccinia — noun Etymology: New Latin, from vaccinus Date: 1803 1. a poxvirus (species Vaccinia virus of the genus Orthopoxvirus) that differs from but is closely related to the viruses causing smallpox and cowpox and that includes a strain of uncertain… …   New Collegiate Dictionary

  • vaccinia — vaccinial, adj. /vak sin ee euh/, n. 1. a variant of the cowpox virus that became established in vaccines derived from cowpox inoculated humans. 2. Pathol. an acute infection caused by inoculation with vaccinia virus as a prophylactic against… …   Universalium

  • vaccinia — Virus of the Orthopoxvirus family used in vaccination against smallpox. Related to, but not identical to, cowpox virus. Also used as a vector for introducing DNA into animal cells …   Dictionary of molecular biology

  • vaccinia — noun An infection of cowpox; or the virus which causes this infection …   Wiktionary

  • vaccinia — vac·cin·i·a || væk sɪnɪə n. cowpox disease …   English contemporary dictionary

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