* * *Lyme disease n an acute inflammatory disease that is usu. characterized initially by the skin lesion erythema migrans and by fatigue, fever, and chills and if left untreated may later manifest itself in cardiac and neurological disorders, joint pain, and arthritis and that is caused by a spirochete of the genus Borrelia (B. burgdorferi) transmitted by the bite of a tick esp. of the genus Ixodes (I. scapularis syn. I. dammini in the eastern and midwestern U.S., I. pacificus esp. in some parts of the Pacific coastal states of the U.S., and I. ricinus in Europe) called also Lyme, Lyme borreliosis
* * *a disease caused by a spirochaete, Borrelia burgdorferi, and transmitted by certain ticks of the genus Ixodes. Following a 3-32-day incubation period, a slowly extending red rash develops in approximately 75% of cases; intermittent systemic symptoms include fever, malaise, headache and neck stiffness, and muscle and joint pains. Later, 60% of patients suffer intermittent attacks of arthritis, especially of the knees, each attack lasting months and recurring over several years. The spirochaete has been identified in synovium and synovial fluid. Neurological and cardiac involvement occurs in a smaller percentage of cases. Treatment is with tetracycline or penicillin.
* * *a recurrent, multisystemic disorder caused by the spirochete Borrelia burgdorferi; vectors for human infection are the ticks Ixodes scapularis and I. pacificus. It begins in most cases with erythema chronicum migrans (at least 5 cm in diameter), which is followed by highly variable manifestations that may include myalgia, arthritis of large joints, stiff neck, involvement of the nervous and cardiovascular systems, and systemic symptoms such as chills, fever, headache, malaise, and vomiting.
Medical dictionary. 2011.
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