LOD score

In genetics, a statistical estimate of whether two loci (the sites of genes) are likely to lie near each other on a chromosome and are therefore likely to be inherited together as a package. LOD stands for logarithm of the odds (to the base 10). A LOD score of three or more is generally taken to indicate that two gene loci are close to each other on the chromosome. (A LOD score of three means the odds are a thousand to one in favor of genetic linkage).
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A number used in genetic linkage studies; logarithm (decadic) of the odds in favor of genetic linkage. [logarithm + odds]

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lod score 'läd-.skō(ə)r, 'lȯd-, -.skȯ(ə)r n [logarithmic odds score] a statistic that is used to detect genetic linkage and that is equal to the logarithm to base 10 of the ratio of the probability that the data in a linkage experiment would be obtained if the genetic loci under investigation were linked to the probability that the data would be obtained if the loci were not linked

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[logarithm of the odds favoring linkage] a score that measures the likelihood of two genes showing a specified recombination value, indicating linkage.

Medical dictionary. 2011.

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  • lod score — lod score. Количественный показатель сцепления генов, используемый в случаях отсутствия исчерпывающей информации по наследованию данных генов в больших родословных <pedigree>; lod score (logarithm of the odd ratio) равен: P(Fir) еilog ,… …   Молекулярная биология и генетика. Толковый словарь.

  • Lod score — Liaison génétique La liaison génétique (ou genetic linkage) désigne le fait que deux allèles de deux gènes différents sont transmis ensemble d un individu à sa descendance. Attention à distinguer liaison génétique de liaison physique : deux… …   Wikipédia en Français

  • LOD-Score — In der Genetik wird der LOD Score als statistische Abschätzung der Wahrscheinlichkeit herangezogen, ob zwei Loci (Genorte) auf demselben Chromosom nah beieinander liegen und somit gekoppelt vererbt werden. LOD steht für logarithm of the odds oder …   Deutsch Wikipedia

  • LOD score — In der Genetik wird der LOD Score als statistische Abschätzung der Wahrscheinlichkeit herangezogen, ob zwei Loci (Genorte) auf demselben Chromosom nah beieinander liegen und somit gekoppelt vererbt werden. LOD steht für logarithm of the odds oder …   Deutsch Wikipedia

  • Lod score — ‘Logarithm of the odds’ score: a statistical test for the probability that there is linkage. For non X linked genetic disorders a Lod score of +3 (1000:1) is usually taken to indicate linkage …   Dictionary of molecular biology

  • lod score — The logarithm of the odds of linkage between two loci. Used to measure the statistical support for linkage …   Glossary of Biotechnology

  • Lod (disambiguation) — Lod is a city in Israel. Lod, LOD and LoD may also refer to:* , an official expansion to the computer game Diablo II . *Law of Demeter, a design guideline for developing software. *Legacy of Darkness *Length on deck, a measurement of a ship over… …   Wikipedia

  • LOD-оценка — * LOD ацэнка * LOD Score 1. Статистическая величина, показывающая насколько велика вероятность того, что два локуса одной хромосомы находятся достаточно близко друг от друга и могут наследоваться вместе. Если эта величина равна 3 и больше, то это …   Генетика. Энциклопедический словарь

  • LoD — Das Kürzel LOD oder LoD kann für folgende Bedeutungen stehen: Legion of Doom, eine Gruppe aus der Hackerszene Law of Demeter, eine Entwurfsrichtlinie in der Softwareentwicklung Level of Detail, in Echtzeit 3D Anwendungen eingesetztes Verfahren… …   Deutsch Wikipedia

  • LOD — El término LOD puede referirse a: Luis Ortiz (LOD), músico de minimal. LOD, grupo musical de hip hop. LOD score, log of odds score, hace referencia a un test estadístico que se utiliza para análisis de ligamiento en genética de poblaciones. Esta… …   Wikipedia Español

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