testosterone

The most potent naturally occurring androgen, formed in greatest quantities by the interstitial cells of the testes, and possibly secreted also by the ovary and adrenal cortex; may be produced in nonglandular tissues from precursors such as androstenedione; used in the treatment of hypogonadism, cryptorchism, certain carcinomas, and menorrhagia.
- t. cypionate a preparation with the same actions and uses as t. propionate, but with a prolonged duration of action.
- t. enanthate a preparation with the same actions and uses as t., but with a prolonged duration of action, being administered in oil.
- t. phenylpropionate an alternate preparation for the propionate.
- t. propionate a preparation that has an action similar to but more pronounced and prolonged than that of t.; used in the treatment of undescended testes and in menorrhagia.

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tes·tos·ter·one te-'stäs-tə-.rōn n a male hormone that is a crystalline hydroxy steroid ketone C19H28O2 produced primarily by the testes or made synthetically and that is the main androgen responsible for inducing and maintaining male secondary sex characteristics

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n.
the principal male sex hormone (see androgen).

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tes·tos·te·rone (tes-tosґtə-rōn) the major androgenic hormone produced by the interstitial cells (Leydig cells) of the testes in response to stimulation by the luteinizing hormone of the adenohypophysis; it regulates gonadotropic secretion and wolffian duct differentiation (formation of the epididymis, vas deferens, and seminal vesicle), and stimulates skeletal muscle. It is also responsible for other male characteristics and spermatogenesis after its conversion to dihydrotestosterone (q.v.) by 5α-reductase in peripheral tissue. In addition, testosterone possesses protein anabolic properties, manifested by retention of nitrogen, calcium, phosphorus, and potassium, and is important in maintaining muscle mass and bone tissue in the adult male. It is also converted by aromatization to estradiol in peripheral tissue. See also anabolic-androgenic steroids, under steroid. [USP] the same principle prepared synthetically from cholesterol or isolated from bull testes, used as the base or various esters in treating primary and secondary male hypogonadism and delayed male puberty, and in palliation of metastatic breast carcinoma in postmenopausal women; its derivatives may be used for their anabolic properties. Administered by subcutaneous implantation, transdermal delivery, or intramuscular injection.

Medical dictionary. 2011.

Look at other dictionaries:

  • Testosterone — Testostérone  Pour l’article homonyme, voir Testostérone (émission).  Testostérone …   Wikipédia en Français

  • testostérone — [ tɛstosterɔn ] n. f. • 1935; de test(icule), stér(ol) et (horm)one ♦ Biochim. Hormone mâle sécrétée par les testicules, qui stimule le développement des organes génitaux mâles et détermine l apparition des caractères sexuels mâles secondaires.… …   Encyclopédie Universelle

  • Testosterone — Tes*tos ter*one (t[e^]s*t[o^]s t[ e]r*[=o]n), n. [testes + o + sterone a steroid ketone.] a steroid hormone ({C19H28O2}) produced mostly in the testes, which is responsible for producing the secondary sexual characteristics of males. [PJC] …   The Collaborative International Dictionary of English

  • testosterone — testosterone. См. тестостерон. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • testosterone — (n.) male sex hormone, 1935, from Ger. Testosteron (1935), coined from a presumed comb. form of L. testis testicle (see TESTIS (Cf. testis)) + ster(ol) (see STEROID (Cf. steroid)) + chemical ending ONE (Cf. one) …   Etymology dictionary

  • testosterone — ► NOUN ▪ a steroid hormone stimulating development of male secondary sexual characteristics. ORIGIN from TESTIS(Cf. ↑testis) …   English terms dictionary

  • testosterone — [tes täs′tər ōn΄] n. [ TEST(IS) + O + STER(OL) + ONE] a male, steroid sex hormone, C19H28O2, produced as a white, crystalline substance by isolation from animal testes, or synthesized: used in medicine …   English World dictionary

  • Testosterone — For the film, see Testosterone (film). Testosterone Systematic (IUPAC) name …   Wikipedia

  • Testostérone —  Pour l’article homonyme, voir Testostérone (émission).  Testostérone …   Wikipédia en Français

  • testosterone — /tes tos teuh rohn /, n. 1. Biochem. the sex hormone, C19H28O2, secreted by the testes, that stimulates the development of male sex organs, secondary sexual traits, and sperm. 2. Pharm. a commercially prepared form of this compound, originally… …   Universalium

  • testosterone — n. the principal male sex hormone (see androgen). Formed from androstenedione within the interstitial cells of the testis, it is converted in target cells to dihydrotestosterone, which mediates most of its actions. Preparations of testosterone… …   The new mediacal dictionary

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