- dextrocardia (heart on the right side), and infertility. The syndrome is inherited in an autosomal recessive manner. Kartagener syndrome is usually due to mutation in the gene called DNAI1 (axonemal dynein intermediate chain) which is in chromosome region 9p21-p13. However, linkage studies have mapped the disease gene to 5p and 19q in some families, indicating that Kartagener syndrome is more than one genetic entity.
* * *a hereditary disorder involving a combination of dextrocardia (situs inversus), bronchiectasis, and sinusitis, transmitted as an autosomal recessive trait.
Medical dictionary. 2011.
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Kartagener syndrome (triad) — Kar·tag·e·ner syndrome (triad) (kahr tagґə nər) [Manes Kartagener, Swiss physician, 1897â€“1975] see under syndrome … Medical dictionary
Syndrome de kartagener — Autre nom Dyskinésie ciliaire primitive Référence MIM … Wikipédia en Français
Syndrome de Kartagener — Référence MIM 244400 Transmission Récessive Chromosome 5p15 p14 7p21 9p21 p13 Gène DNAI1 DNAH5 DNAH11 Mutation … Wikipédia en Français
Kartagener's syndrome — Kar·ta·ge·ner s syndrome kär tä gə nərz , .kär tə gā nərz n an abnormal condition inherited as an autosomal recessive trait and characterized by situs inversus, abnormalities in the protein structure of cilia, and chronic bronchiectasis and… … Medical dictionary
syndrome — The aggregate of symptoms and signs associated with any morbid process, and constituting together the picture of the disease. SEE ALSO: disease. [G. s., a running together, tumultuous concourse; (in med.) a concurrence of symptoms, fr. syn,… … Medical dictionary
Kartagener's syndrome — a hereditary condition in which the heart and other internal organs lie on the opposite side of the body to the norm (i.e. the heart lies on the right; see dextrocardia); it is associated with chronic sinusitis and bronchiectasis [Kartagener… … The new mediacal dictionary
Kartagener's syndrome — (= situs inversus) Condition in which the normal left/right asymmetry of the viscera is reversed. Associated with a dynein defect (dynein is absent or dysfunctional in some cases) and with immotile cilia syndrome … Dictionary of molecular biology
Kartagener — Manes, Swiss physician, 1897–1975. See K. syndrome, K. triad … Medical dictionary
Kartagener triad — see under syndrome … Medical dictionary
Syndrome, Kartageners — The trio of sinusitis, bronchitis and situs inversus (lateral reversal of the position all organs in the chest and abdomen with the heart and stomach on the right, the liver on the left, etc.opposite or "inverted" from their usual … Medical dictionary