selectin

A cell surface molecule involved in immune adhesion and cell trafficking. [L. se-ligo, pp. se-lectum, to sort, choose, + -in]
- E s. cell surface receptor produced by endothelium.
- L s. cell surface receptor produced by leukocytes.
- P s. cell surface receptor present on endothelium that is involved with neutrophil migration into inflamed tissue.

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se·lec·tin sə-'lek-tin n any of a family of sugar-binding lectins that are found on the surface of cells (as endothelial cells and white blood cells) and that promote their adhesion to other cells and mediate their migration to sites of inflammation

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se·lec·tin (sə-lekґtin) any of a family of cell adhesion molecules consisting of a lectin-like domain, an epidermal growth factor–like domain, and a variable number of domains that encode proteins homologous to complement-binding proteins; their function is to mediate the binding of leukocytes to the vascular endothelium.

Medical dictionary. 2011.

Look at other dictionaries:

  • Selectin — Selectins are a family of cell adhesion molecules (or CAMs). All selectins are single chain transmembrane glycoproteins that share similar properties to C type lectins due to a related amino terminus and calcium dependent bindingcite book | title …   Wikipedia

  • Selectin — Selectine (auch Selektine) sind Glykoproteine in den Plasmamembranen bestimmter eukaryotischer Zellen. Sie gehören zur Gruppe der Zelladhäsionsmoleküle (CAMs, Cell Adhesion Molecules). Typen Drei Typen von Selectinen sind bekannt: E , P und L… …   Deutsch Wikipedia

  • selectin — Group of cell adhesion molecules that bid to carbohydrates via a lectin like domain. The name is derived from select and lectin. They are integral membrane glycoproteins with an N terminal, C type lectin domain, followed by an EGF like domain, a… …   Dictionary of molecular biology

  • selectin — noun Any of a group of transmembrane glycoproteins important in cell adhesion …   Wiktionary

  • Selectin — Se|lec|tin [zu ↑ selektiv (?) u. ↑ Lectin], das; s, e; S: Selektin: Sammelbez. für lectinähnliche körpereigene Membranproteine (P , E u. L S.), die sich z. B. bei Entzündungen aufgrund ihrer kohlenhydraterkennenden Eigenschaften an Zellen… …   Universal-Lexikon

  • P-selectin glycoprotein ligand-1 — Selectin P ligand Identifiers Symbols SELPLG; CD162; CLA; PSGL 1; PSGL1 External IDs …   Wikipedia

  • P-selectin — Selectin P (granule membrane protein 140kDa, antigen CD62) PDB rendering based on pdb 1gsr …   Wikipedia

  • L-selectin — L selectin, also known as CD62L, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognise sialylated carbohydrate groups. It is cleaved by ADAM17. PBB Summary section title = summary text =… …   Wikipedia

  • E-selectin — E selectin, also known as CD62E, is a cell adhesion molecule expressed only on endothelial cells activated by cytokines. Like other selectins, it plays an important part in inflammation. Ligands E selectin recognises and binds to sialylated… …   Wikipedia

  • E-Selectin — Selectine (auch Selektine) sind Glykoproteine in den Plasmamembranen bestimmter eukaryotischer Zellen. Sie gehören zur Gruppe der Zelladhäsionsmoleküle (CAMs, Cell Adhesion Molecules). Typen Drei Typen von Selectinen sind bekannt: E , P und L… …   Deutsch Wikipedia

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