Infection, rotavirus

A leading cause of severe winter diarrhea in young children. Each year, rotavirus (RV) causes an estimated 500,000 doctor visits and 50,000 hospital admissions in the United States. Almost every child catches RV before entering school but, with rehydration (and good nutrition), nearly all recover fully. However, in poor countries RV is estimated to be responsible for at least 600,000 deaths of children under 5 years from RV diarrhea and dehydration yearly. Aside from causing acute infantile gastroenteritis and diarrhea in young children, RV infection is typically accompanied by low-grade fever. A vaccine against RV has been found to provide a high level of protection against severe diarrhea caused RV. A report to this effect appeared in The New England Journal of Medicine (vol. 337, pp. 1181-7, 1997). The RV vaccine was licensed by the U.S. Food and Drug Administration (FDA) in August, 1998. However, in July of 1999 the Centers for Disease Control and Prevention (CDC) and the American Academy of Pediatrics (AAP) jointly recommended that rotavirus vaccination be postponed until November, 1999. This recommendation was made as a precaution because of some reports of intussception (telescoping of the intestine resulting in intestinal obstruction) in infants who had had rotavirus vaccination. Rotavirus was discovered in 1973 and took its name from its wheel-

Medical dictionary. 2011.

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  • Rotavirus (RV) — A leading cause of severe winter diarrhea in young children, RV each year causes an estimated 500,000 doctor visits and 50,000 hospital admissions in the United States. Almost everyone catches RV before entering school but, with rehydration (and… …   Medical dictionary

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  • rotavirus — A group of RNA viruses (family Reoviridae) wheel like in appearance that form a genus, Rota virus, which includes the human gastroenteritis viruses (a major cause of infant diarrhea throughout the world). Separated into groups A …   Medical dictionary

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  • rotavirus gastroenteritis — viral gastroenteritis due to a rotavirus infection, one of the most common causes of diarrhea in the United States; the virus is usually ingested in contaminated food or water. Young children are particularly susceptible and can suffer severe… …   Medical dictionary

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