pyrimethamine

A potent folic acid antagonist used as an antimalarial agent effective against Plasmodium falciparum; a valuable suppressant, active against the asexual erythrocytic and tissue forms; also used in the treatment of toxoplasmosis.

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py·ri·meth·amine .pī-rə-'meth-ə-.mēn n a folic acid antagonist C12H13ClN4 that is used in the treatment of toxoplasmosis and the prevention of malaria

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n.
a drug administered by mouth for the prevention and treatment of malaria, either alone or in combination with dapsone (in Maloprim); it is also used in the treatment of toxoplasmosis. Possible side-effects include loss of appetite and vomiting, and prolonged use may interfere with red blood cell production. Trade name: Daraprim.

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pyr·i·meth·amine (pir″ĭ-methґə-mēn) [USP] a folic acid antagonist, used as an antimalarial, especially for suppressive prophylaxis, and also used concomitantly with a sulfonamide in the treatment of toxoplasmosis, administered orally.

Medical dictionary. 2011.

Look at other dictionaries:

  • Pyrimethamine — Systematic (IUPAC) name 5 (4 chlorophenyl) 6 ethyl 2,4 pyrimidinediamine Clinical data Trade names Daraprim …   Wikipedia

  • Pyrimethamine — Molécule de Pyriméthamine Général Nom IUPAC 5 (4 Chlorophenyl) 6–ethyl–2,4–pyrimidinediamine …   Wikipédia en Français

  • Pyriméthamine — Molécule de pyriméthamine Général Nom IUPAC 5 (4 chlorophényl) 6–éthyl–2,4–pyrimidinediamine …   Wikipédia en Français

  • pyrimethamine — n. a drug administered by mouth in combination with the sulphonamide sulfadoxine (as Fansidar) for the treatment of malignant (falciparum) malaria. It is also used, in combination with sulfadiazine, in the treatment of toxoplasmosis. Possible… …   The new mediacal dictionary

  • pyrimethamine — noun Etymology: pyrimidine + ethyl + amine Date: 1952 a folic acid antagonist C12H13ClN4 used in the chemoprophylaxis or treatment of malaria and in the treatment of toxoplasmosis …   New Collegiate Dictionary

  • pyrimethamine — /puy reuh meth euh meen , min/, n. Pharm. a potent substance, C12H13ClN4, used against susceptible plasmodia in the prophylactic treatment of malaria and against Toxoplasma gondi in the treatment of toxoplasmosis. [1950 55; PYRIM(IDINE) + ETH(YL) …   Universalium

  • pyrimethamine — noun a folic acid antagonist, used in the prophylactic treatment of malaria …   Wiktionary

  • pyrimethamine — py·ri·meth·amine …   English syllables

  • pyrimethamine — ˌpirə̇ˈmethəˌmēn, ˌpīr noun Etymology: pyrimidine + ethyl + amine : a folic acid antagonist C12H13ClN4 used in the treatment of malaria and toxoplasmosis …   Useful english dictionary

  • Пириметамин (Pyrimethamine) — лекарственное вещество; назначается внутрь для предотвращения развития и лечения малярии; может применяться как отдельно, так и в сочетании с дапсоном (в таком препарате, как малоприм (Maloprim)); кроме того, используется для лечения… …   Медицинские термины

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