Low blood levels of chloride. Chloride is the major anion found in the fluid outside of cells and in blood. An anion is the negatively charged part of certain substances such as table salt (NaCl) when dissolved in liquid. Sea water has almost the same concentration of chloride ion as human fluids. The balance of chloride ion (Cl-) is closely regulated by the body. Significant decreases in chloride can have deleterious or even fatal consequences. Chloride is normally lost in the urine, sweat, and stomach secretions. Excessive loss can occur from heavy sweating, vomiting, and adrenal gland and kidney disease. The normal serum range for chloride is 98 - 108 mmol/L.
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An abnormally low level of chloride ions in the circulating blood.

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hy·po·chlor·emia or chiefly Brit hy·po·chlor·ae·mia .hī-pō-klōr-'ē-mē-ə, -klȯr- n abnormal decrease of chlorides in the blood

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hy·po·chlor·emia (hi″po-klor-eґme-ə) abnormally low levels of chloride in the blood. hypochloremic adj

Medical dictionary. 2011.

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