pregnenolone

3β-Hydroxy-5-pregnen-20-one; a steroid that serves as an intermediate in the biosynthesis of numerous hormones, including progesterone.

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preg·nen·o·lone preg-'nen-əl-.ōn n an unsaturated hydroxy steroid ketone C21H32O2 that is formed by the oxidation of steroids (as cholesterol) and yields progesterone on dehydrogenation

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n.
a steroid synthesized in the adrenal glands, ovaries, and testes. Pregnenolone is an important intermediate product in steroid hormone synthesis and can - depending on the pathways followed - be converted to corticosteroids (glucocorticoids or mineralocorticoids), androgens, or oestrogens.

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preg·ne·no·lone (preg-nēnґə-lōn) 1. an intermediate compound in the synthesis of steroid hormones, formed by cleavage of the side chain of cholesterol between C-20 and C-22. 2. a synthetic preparation of this hormone, used in treatment of rheumatoid arthritis.

Medical dictionary. 2011.

Look at other dictionaries:

  • Pregnenolone — Prégnénolone Prégnénolone Structure chimique Général No CAS …   Wikipédia en Français

  • Prégnénolone — Structure chimique Général Nom IUPAC 17 acétyl 10,13 diméthyl 2,3,4,7,8,9,11,12,14,15,16,17 dodécahydro 1H cyclopenta[a]phénanthrén 3 ol …   Wikipédia en Français

  • Pregnenolone — drugbox IUPAC name = 3β hydroxypregn 5 en 20 one CAS number = 145 13 1 ATC prefix = ATC suffix = ATC supplemental = PubChem = 8955 DrugBank = EXPT02608 C=21 | H=32 | O=2 molecular weight = 316.483 g/mol bioavailability = protein bound =… …   Wikipedia

  • pregnenolone — n. a steroid synthesized in the adrenal glands, ovaries, and testes. Pregnenolone is an important intermediate product in steroid hormone synthesis and can – depending on the pathways followed – be converted to corticosteroids (glucocorticoids or …   The new mediacal dictionary

  • pregnenolone — noun Etymology: International Scientific Vocabulary pregnene (C21H34) + 1 ol + one Date: 1936 an unsaturated hydroxy steroid ketone C21H32O2 that is formed by the oxidation of steroids (as cholesterol) and yields progesterone on dehydrogenation …   New Collegiate Dictionary

  • pregnenolone — noun A steroid prohormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens …   Wiktionary

  • pregnenolone — preg·nen·o·lone …   English syllables

  • pregnenolone — pregˈnēnəlˌōn noun ( s) Etymology: International Scientific Vocabulary pregnene + ol + one : a crystalline unsaturated hydroxy steroid ketone C21H32O2 formed by the oxidation of cholesterol (as in living cells), stigmasterol, diosgenin, or other… …   Useful english dictionary

  • pregnenolone succinate — a nonhormonal sterol derivative that has been used in treatment of rheumatoid arthritis …   Medical dictionary

  • Прегненолон (Pregnenolone) — стероид, который синтезируется в надпочечниках, яичниках и яичках. Прегненолон является важным промежуточным продуктом процесса синтеза стероидного гормона и может (в зависимости от пути своего следования) превращаться в кортикостероиды… …   Медицинские термины

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