polyadenylation

1. The process of formation of poly(adenylic acid). 2. The covalent modification of a macromolecule ( E.G., mRNA) by the formation of a polyadenylyl moiety covalent linked to the macromolecule.

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poly·aden·y·la·tion (pol″e-ə-den″ə-laґshən) the formation of the polyadenylate tail on eukaryotic RNA molecules or at the 3ґ end of viral mRNA, catalyzed by polynucleotide adenylyltransferase.

Medical dictionary. 2011.

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  • polyadenylation — polyadenylation. См. полиаденилирование. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Polyadenylation — Typical structure of a mature eukaryotic mRNA Polyadenylation is the addition of a poly(A) tail to an RNA molecule. The poly(A) tail consists of multiple adenosine monophosphates; in other words, it is a stretch of RNA that has only adenine bases …   Wikipedia

  • Polyadénylation — La polyadénylation consiste en l addition d une queue poly (A), une succession de nombreux ribonucléotides de type Adénosine (A) à l extrémité 3 des ARNm[1]. Chez les eucaryotes, cette étape s effectue dans le noyau, lors de sa maturation… …   Wikipédia en Français

  • polyadenylation — noun The formation of a polyadenylate, especially that of a nucleic acid …   Wiktionary

  • polyadenylation — poly·ad·e·nyl·a·tion …   English syllables

  • polyadenylation — Post transcriptional addition of multiple adenine residues to the 3 end of eukaryotic mRNA. Also called poly (A) tailing. The adenine rich 3 terminal segment is called a poly (A) tail …   Glossary of Biotechnology

  • polyadenylation — noun see polyadenylate …   Useful english dictionary

  • Cleavage and polyadenylation specificity factor — (CPSF) (or Cleavage polyadenylation stimulating factor) is involved in the cleavage of the 3 signaling region from a newly synthesized pre messenger RNA (pre mRNA) molecule in the process of gene transcription. It is the first protein to bind to… …   Wikipedia

  • Simian virus 40 late polyadenylation signal (SVLPA) — The simian virus 40 late polyadenylation signal (SVLPA) is an RNA element which promotes efficient polyadenylation. [cite journal | last = Wu | first = C | coauthors = Alwine JC | year = 2004 | title = Secondary structure as a functional feature… …   Wikipedia

  • U1A polyadenylation inhibition element (PIE) — The U1A polyadenylation inhibition element (PIE) is an RNA element which is responsible for the regulation of the length of the polyA tail of the U1A protein pre mRNA. The PIE is located in the U1A mRNA 3 UTR. PIE adopts a U shaped structure,… …   Wikipedia

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