- * * *- Langerhans cell h. a set of closely related disorders unified by a common proliferating element, the Langerhans cell. Three overlapping clinical syndromes are recognized: a single site disease (eosinophilic granuloma), a multifocal unisystem process (Hand-Schuller-Christian syndrome), and a multifocal, multisystem h. (Letter-Siwe syndrome.) Formerly this process was known as h. X. SYN: h. X.- lipid h. h. with cytoplasmic accumulation of lipid, either phospholipid (Niemann-Pick disease) or glucocerebroside (Gaucher disease).- malignant h. a rapidly fatal form of lymphoma, characterized by fever, jaundice, pancytopenia, and enlargement of the liver, spleen, and lymph node s; the affected organs show focal necrosis and hemorrhage, with proliferation of histiocytes and phagocytosis of red blood cells.- nonlipid h. SYN: Letterer-Siwe disease.- sinus h. with massive lymphadenopathy a chronic disease occurring in children and characterized by massive painless cervical lymphadenopathy due to distension of the lymphatic sinuses by macrophages containing ingested lymphocytes, and by capsular and pericapsular fibrosis. SYN: Rosai-Dorfman disease.- h. Y SYN: verrucous xanthoma.
* * *his·tio·cy·to·sis -'tō-səs n, pl -to·ses -.sēz abnormal multiplication of macrophages <Langerhans cell \histiocytosis> broadly a condition characterized by such multiplication
* * *n.any of a group of diseases in which there are abnormalities in certain large phagocytic cells (histiocyte) due to (1) abnormal storage of fats, as in Gaucher's disease; (2) inflammatory disorders, as in Langerhans cell histiocytosis, which includes disorders previously called histiocytosis X; or (3) malignant proliferation of histiocytes.
* * *his·tio·cy·to·sis (his″te-o-si-toґsis) any of a variety of proliferative disorders of macrophages (histiocytes), marked by the abnormal appearance of macrophages in the blood, or by abnormally elevated numbers of macrophages in lymphoid tissue.
Medical dictionary. 2011.
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Histiocytosis — Classification and external resources ICD 10 C96.1, D76.0 ICD 9 … Wikipedia
Histiocytosis — vgl. Histiozytose … Das Wörterbuch medizinischer Fachausdrücke
Histiocytosis X — Klassifikation nach ICD 10 C96.0 Abt Letterer Siwe Krankheit Letterer Siwe Syndrom C96.1 Maligne Histiozytose D76.0 … Deutsch Wikipedia
histiocytosis — n. any of a group of diseases in which there are abnormalities in certain large phagocytic cells (histiocytes) due to 1) abnormal storage of fats, as in Gaucher s disease; 2) inflammatory disorders, as in Langerhans cell histiocytosis, which… … The new mediacal dictionary
histiocytosis — his·ti·o·cy·to·sis (hĭs tē ō sī tōʹsĭs) n. pl. his·ti·o·cy·to·ses ( sēz) Any of several abnormal conditions characterized by the appearance of histiocytes in the blood or tissues. * * * … Universalium
histiocytosis X — Langerhans cell h … Medical dictionary
histiocytosis — his·tio·cy·to·sis … English syllables
histiocytosis — noun a blood disease characterized by an abnormal multiplication of macrophages • Hypernyms: ↑blood disease, ↑blood disorder • Hyponyms: ↑Hand Schuller Christian disease, ↑Schuller Christian disease … Useful english dictionary
Histiocytosis, Langerhans cell — Histiocytosis in which the active histiocytes normally occur in the skin. See histiocytosis … Medical dictionary
Histiocytosis, malignant — Histiocytosis in which the histiocytes actually become cancerous. Treatment is by radiation and chemotherapy, and in some cases bone marrow transplantation. See also histiocytosis … Medical dictionary