Its former use in gout was based upon its property of dissolving uric acid in vitro, but it is ineffective in increasing uric acid excretion; its compounds are now used as anthelmintics in oxyuriasis and ascariasis. SYN: diethylenediamine.
- p. adipate a veterinary anthelmintic and filaricide.
- p. citrate a vermifuge for pinworms and roundworms.
- p. estrone sulfate a purified preparation of natural estrone sulfate; the p. acts as a buffer to increase the stability of estrone sulfate.
- p. tartrate an anthelmintic useful in the treatment of nematode infestation.

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pi·per·a·zine pī-'per-ə-.zēn n a crystalline heterocyclic base C4H10N2 or C4H10N2·6H2O used esp. as an anthelmintic

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a drug used to treat infestations by roundworms and threadworms. It is administered by mouth; side-effects do not usually occur, but continued treatment at high doses may cause nausea, vomiting, headache, tingling sensations, and rashes. Trade name: Pripsen.

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pi·per·a·zine (pi-perґə-zēn) [USP] an anthelmintic effective against the parasites Ascaris lumbricoides and Enterobius vermicularis; it causes a flaccid paralysis of the worm musculature by altering cell membrane permeability and causing hyperpolarization of the membrane. Called also diethylenediamine and piperazidine.

Medical dictionary. 2011.

Look at other dictionaries:

  • Piperazine — Piperazine[1] …   Wikipedia

  • Piperazine — Pipérazine Pipérazine Structure de la pipérazine Général Nom IUPAC Pipérazine …   Wikipédia en Français

  • Pipérazine — Structure de la pipérazine Général Nom IUPAC Pipérazine …   Wikipédia en Français

  • pipérazine — ● pipérazine nom féminin Dénomination courante de l hexahydropyrazine. (Longtemps employée dans le traitement de la goutte et de la lithiase urique, la pipérazine est utilisée actuellement pour le traitement des parasitoses intestinales dues aux… …   Encyclopédie Universelle

  • Piperazine — Pi*per a*zine, n. Also zin zin . [Piperidine + azote + ine.] (Chem.) A crystalline substance, {(C2H4NH)2}, formed by action of ammonia on ethylene bromide, by reduction of pyrazine, etc. It is a strong base, and is used as a remedy for gout.… …   The Collaborative International Dictionary of English

  • piperazine — [pi per′ə zēn΄, pīper′ə zēn΄; pi per′əzin, pī per′əzin; pip′ər əzēn, pip′ər əzin] n. [ PIPER(INE) + AZ + INE3] a crystalline compound, (C2H4NH) 2, used in treating worm infestations, in insecticides, etc …   English World dictionary

  • piperazine — piperazinas statusas T sritis chemija apibrėžtis Heterociklinis junginys. formulė Formulę žr. priede. priedas( ai) Grafinis formatas atitikmenys: angl. piperazine rus. пиперазин ryšiai: sinonimas – heksahidropirazinas …   Chemijos terminų aiškinamasis žodynas

  • piperazine — noun Etymology: International Scientific Vocabulary piperidine + azine Date: 1889 a crystalline heterocyclic base C4H10N2 used especially as an anthelmintic …   New Collegiate Dictionary

  • piperazine — /pi per euh zeen , zin, puy , pip euhr euh /, n. Chem. 1. Also called piperazidine /pip euh raz i deen , din, puy peuh /. a colorless, crystalline, deliquescent ring compound, C4H10N2, prepared by the reaction of ethylene bromide or ethylene… …   Universalium

  • piperazine — noun /pɪˈpɛɹəziːn/ a) A saturated heterocyclic compound, CHN, containing two nitrogen atoms in a six membered ring; it is used as an anthelmintic. b) Any derivative of this compound …   Wiktionary

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